Article Summary
赵欣杨志杰.甲状腺癌肿瘤标志物研究进展[J].现代生物医学进展英文版,2011,11(21):4191-4193.
甲状腺癌肿瘤标志物研究进展
Progress of Tumor Markers in Thyroid Cancer
  
DOI:
中文关键词: 甲状腺癌  肿瘤标志物  肿瘤转移
英文关键词: Thyroid cancer  Tumor marker  Neoplasm metastasis
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Author NameAffiliation
ZHAO Xin, YANG Zhi-jie 哈尔滨医科大学附属第一医院核医学科 
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中文摘要:
      甲状腺癌肿瘤标志物是由甲状腺癌组织和细胞产生的异常表达的生物活性物质。近年来,肿瘤标志物成为肿瘤基础和临床 应用的一个非常活跃的领域,其不仅与甲状腺癌的形成、发展和转移关系密切,也对它的诊断和治疗具有重要意义。随着研究的 不断深入,这些肿瘤标志物在临床上已显示出了广阔的应用前景。本文就近年来研究较多且与甲状腺癌密切相关的肿瘤标志物, 包括Galectin-3,CK-19,VEGF,端粒酶和端粒酶逆转录酶,MMPs,降钙素,E-cadherin,Tg,TSHR mRNA进行综述。
英文摘要:
      Tumor markers of thyroid cancer are bioactive substance by thyroid cancer tissue and cell abnormal expression. In recent years, tumor marker has been a highly active area in basic research and clinical investigation of oncology. These tumor markers in thyroid cancer not only closely relate to the genesis, development and metastasis, but also play a part in diagnosis and treatment. With the deepening of the study, these tumor markers in clinical practice has shown broad prospects. In this paper we review recent empirical studies of tumor markers that is closely related to thyroid cancer, including the Galectin-3, CK-19, VEGF, telomerase and telomerase reverse transcriptase, MMPs, calcitonin, E-cadherin, Tg, TSHR mRNA.
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