| 杨燕1 刘会玲2 虎镯3 高飞艳4 杨毓琴2.兰州地区女性感染HPV及其基因类型分析[J].现代生物医学进展英文版,2011,11(21):4069-4071. |
| 兰州地区女性感染HPV及其基因类型分析 |
| Study on the Human Papillomavirus (HPV) Infection and GenotypesDistribution Pattern ofWomen in Lanzhou Area |
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| DOI： |
| 中文关键词: 人乳头瘤病毒(HPV) 分型 PCR |
| 英文关键词: Human papillomavirus (HPV) Genotyping PCR |
| 基金项目: |
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| 中文摘要: |
| 目的：了解兰州地区成年女性感染人乳头瘤病毒( human pap illoma virus, HPV)及其基因类型分布状况，为本地区HPV 分子
流行病学研究提供理论依据。方法：利用PCR技术分别对100例妇科门诊就诊者进行HPV基因亚型检测。结果：100例样品中，
HPV DNA检出率为19%（19/100），其中HPV16 DNA感染率15%（15/100），HPV58 DNA 感染率3%（3/100），HPV18 DNA 感染率
2%（2/100），HPV 16与HPV18双重感染1例。结论：本地区成年女性HPV 感染主要以HPV16 多见，而HPV16 与恶性肿瘤密切
相关，因此对HPV DNA阳性者定期随访，有利于宫颈癌的防治。 |
| 英文摘要: |
| Objective: This is an epidemiological study on the distribution pattern of HPV genolypes in Lanzhou area. Methods:
One hundred samples were detected for HPV genotyping by using PCR technique. Results: In 100 samples, the positive rate of HPV
DNA was 19%. HPV16 DNA was 15 % (15/100). HPV58 DNA was 3%(3/100) and HPV18 DNA was 2 %(2/100). And one case infected
both HPV16 and HPV18. Conclusion: The most prevalent HPV genotypes in Lanzhou area were HPV 16 which is closely related with
the malignancy. Therefore peoples who suffered HPV DNA positive should be regularly followed-up, which is useful for the prevention
and treatment of cervical cancer. |
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