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目的：探讨肝移植术后并发急性肾功能衰竭（ARF）的相关因素，为肝移植术后ARF 的预防和治疗提供参考。方法：回顾性分析了2005 年1 月~2010 年10 月在我院行肝移植术的98 例患者的临床资料，对术后并发ARF 的相关因素进行分析。结果：98 例行肝移植术后发生ARF 13 例，发生率为13.27%。单因素分析显示术前血尿素氮（BUN）、术前血清肌酐（Scr）、术前血清白蛋白（Alb）、手术时间、失血量与ARF 的发生有关（P<0.05）。多因素Logistic 回归法分析表明，术前Scr 和BUN 是肝移植术后并发 ARF 的危险因素。结论：术前血BUN、血清Scr、血清Alb、手术时间和失血量是肝移植术后并发ARF 主要因素，而术前Scr 和 BUN 水平升高是肝移植术后并发ARF 的危险因素。对上述因素加以重点评估和合理控制，可以控制肝移植术后ARF 的发生。

英文摘要:

Objective: To investigate the related factors in patient with acute renal failure (ARF) after liver transplantation and provide reference for prevention and treatment of ARF after liver transplantation. Methods: A total of 98 patients, undergoing liver transplantation from January 2005 to October 2010, were selected, analyzing and screening the related factors of acute renal failure after liver transplantation by Logistic. Results: 13 cases of 98 patients occurred ARF, the incidence rate of ARF was 13.27%. The single-factor analysis showed that the priorsurgery blood BUN, priorsurgery serum Scr, priorsurgery serum Alb, operative time and blood loss had certain degree of contact with the incidence of ARF after liver transplantation (P<0.05). Multivariate Logistic regression analysis showed that the priorsurgery serum Scr and blood BUN levels increased were risk factors of incidence of ARF after liver transplantation. Conclusion: The priorsurgery blood BUN, priorsurgery serum Scr, priorsurgery serum Alb, operative time and blood loss are the related factors of incidence of ARF after liver transplantation. The priorsurgery serum Scr and blood BUN levels were risk factors of incidence of ARF after liver transplantation. Assessment and control of these factors can reduce the incidence of ARF after liver transplantation.

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