| 边树疆1 朱兵2△ 田广磊2 王秉林2 姜孝奎2 赛力木2.血浆D- 二聚体检测在下肢深静脉血栓诊断中的价值[J].现代生物医学进展英文版,2011,11(19):3764-3766. |
| 血浆D- 二聚体检测在下肢深静脉血栓诊断中的价值 |
| The Value of Plasma D-dimer in the Diagnosis of Deep Venous Thrombosis |
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| DOI： |
| 中文关键词: 深静脉血栓形成 D- 二聚体 高凝状态 |
| 英文关键词: Deep vein thrombosis D-dimer Hypercoagulability |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨血浆D- 二聚体在下肢深静脉血栓形成(DVT)中的诊疗价值。方法：用SYS MEX CA2 1500 全自动血凝分析仪检
测185 例可疑为DVT 患者及60 例健康体检者血浆中纤维蛋白降解产物D- 二聚体水平，比较其D- 二聚体水平与健康体检组的
差别。结果：60 例健康体检者及185 例疑似DVT 患者中18 例患者血浆D- 二聚体含量< 临界值，经下肢彩色多普勒超声检查证
实无一例患有DVT；167 例患者血浆D- 二聚体含量≥临界值,经下肢彩色多普勒超声检查证实DVT 患者150 例,D- 二聚体检测
DVT 的敏感性、特异性、阳性预期值、阴性预期值分别为100%、51.43%、89.82%、100%。结论：血浆D- 二聚体检测具有快速、经济、
无创、可动态监测等优点，可以作为DVT 诊断的排除试验,值得在临床检验诊断中推广应用。 |
| 英文摘要: |
| Objective: To investigate the value of plasma D-dimer in diagnose and treatment of deep venous thrombosis (DVT).
Methods: SYS MEX CA2 1500 automated coagulation analyzer was used to detect the plasma fibrin degradation product D-dimer levels
of 185 cases of patients suspected of DVT and 60 healthy subjects. Compared the D-dimer levels of patients with the healthy group. Results:
Among the 60 cases of healthy persons and 185 cases of suspected DVT patients, 18 patients had plasma D-dimer levels < critical value;
but they were confirmed not suffered from DVT by the lower extremity color Doppler ultrasound examination. Among the other 167 cases
whose plasma D-dimer level ≥ critical value, 150 cases were confirmed having DVT by the lower extremity color Doppler ultrasound
examination, and the sensitivity, specificity, positive predictive value, negative predictive value of D-dimer test for DVT were respectively
100%, 51.43%, 89.82 % and 100%. Conclusion: Plasma D-dimer test is rapid, economic, non-invasive, dynamic monitoring, etc., thus
it could be applied as exclusion test in diagnosis of DVT and worth of popularization in clinic. |
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