| 魏军1 李昌祁2△ 张晶3 张宝华3 李俊4 阴慧清5.糖尿病患者外科手术麻醉的相关多态性及Logistic 分析[J].现代生物医学进展英文版,2011,11(19):3721-3723. |
| 糖尿病患者外科手术麻醉的相关多态性及Logistic 分析 |
| Related Polymorphism and Logistic Analysis of Surgical Anesthesiain Diabetes Patients |
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| DOI： |
| 中文关键词: 糖尿病 手术 麻醉 |
| 英文关键词: Diabetes Surgery Anesthesia |
| 基金项目: |
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| 中文摘要: |
| 目的：研究与探讨糖尿病患者外科手术麻醉的安全性和有效性。方法：糖尿病外科手术患者262 例,采用腰- 硬联合麻醉146
例，全身麻醉116 例。结果：表明腰- 硬联合麻醉组在术中血糖均值水平、胰岛素的平均使用剂量均少于全身麻醉组，有统计学意
义（P < 0. 05）。腰- 硬联合麻醉组麻醉后空腹血糖、餐后血糖、糖化血红蛋白水平增高幅度均小于全身麻醉组，（P<0.05）。通过用
Logistic 回归方程分析影响糖尿病患者麻醉效果的因素除性别无显著相关性，年龄、糖尿病病程、吸烟、饮酒、体重指数均与麻醉效
果有高度相关性（正相关）。结论：糖尿病手术患者采用腰- 硬联合麻醉效果较好。 |
| 英文摘要: |
| Objective: To study and investigate the safety and effectiveness of different ways of anesthesia on the diabetes patients
undergoing surgery. Methods: A total of 262 cases of surgical patients with diabetes were selected.Among the patients, 146 cases were performed
waist and epidural anesthesia and 116 cases , general anesthesia. Results:The perioperative blood sugar level and mean insulin doses
were less in combined spinal and epidural anesthesia group than in general anesthesia group, with statistical significance (P<0.05). In combined
spinal and epidural anesthesia group, the increased extent of fasting and postprandial blood glucose, glycated hemoglobin levels were
less than those in general anesthesia group (P<0.05). Through Logistic regression analysis, factors such as age, smoking, drinking and body
mass index, except for gender, were highly correlated with the anesthesia effect on diabetes patients (positive). Conclusion: Waist and
epidural anesthesia is better for patients with diabetes. |
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