| 潘云虎季志宇陈艺坛陈光熊勇.莫西沙星治疗78 例伤寒的临床疗效观察[J].现代生物医学进展英文版,2011,11(19):3703-3705. |
| 莫西沙星治疗78 例伤寒的临床疗效观察 |
| Moxifloxacin for 78 Cases of Typhoid |
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| DOI： |
| 中文关键词: 莫西沙星 伤寒 左氧氟沙星 临床疗效 |
| 英文关键词: Moxifloxacin Typhoid Levofloxacin Clinical curative effect |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨莫西沙星在伤寒治疗中的临床意义。方法：将我院2008 年6 月至2010 年6 月期间78 例确诊的伤寒患者随机分
为治疗组( 39 例)和对照组( 39 例)，治疗组给予莫西沙星，对照组给予盐酸左氧氟沙星, 均静脉滴注, 每日1 次，体温正常后7 d 停
药。结果：治疗组痊愈率94.8%，总有效率100%；对照组痊愈率92.3%,总有效率100%，两组痊愈率差异无统计学意义( P < 0. 05) ；
治疗组开始退热和体温降至正常的时间均较对照组缩短, 差异有显著意义( P< 0. 05)。治疗组不良反应发生率明显低于对照组
（P<0.05）。结论：莫西沙星在伤寒治疗中具有疗效确切、无复发、副作用少等特点，在治疗非耐药和耐药伤寒中有重要作用，有较好
的临床应用前景。 |
| 英文摘要: |
| Objective: To evaluate the efficiency and safety of moxif loxacin on typhoid patients. Methods: 78 typhoid patients
were randomly divided into trial group and control group, The 39 trial group members were treated with moxifloxacin，In the control
group, 39 patients were treated with levofloxacin, intravenous dripping every day until normal temperature for 7d. Results: After
treatment, the cured rate in the trial group was 94.8%, while for the control group was 92.3%（P > 0.05）. The time of reducing fever and
returning to normal temperature is shorter in the trial group than in the control group, it was significant differences in two group（P<0.05）,
and the treatment of reaction was significant lower in the trial group than in the control group (P<0.05). Conclusion: Moxifloxacin is
effective and safe in the treatment of typhoid patients, and has good prospects in clinical application. |
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