| 桂玲张克强王静.子宫内膜癌组织中PTEN 和MTA1 蛋白的表达及其相关性[J].现代生物医学进展英文版,2011,11(19):3700-3702. |
| 子宫内膜癌组织中PTEN 和MTA1 蛋白的表达及其相关性 |
| Expression of PTEN and MTA1 and their Correlation in the EndometrialCancer |
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| DOI： |
| 中文关键词: 子宫内膜肿瘤 PTEN MTA1 免疫组织化学 |
| 英文关键词: Endometrial cancer PTEN MTA1 Immunohistochemistry |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨子宫内膜癌组织中PTEN 和MTA1 表达及其与子宫内膜癌生物学行为之间的关系。方法：采用免疫组化SP 法检
测130 例子宫内膜癌和40 例正常宫内膜组织中PTEN 和MTA1 的表达水平，并分析两者在子宫内膜癌中的相关性。结果：子宫
内膜癌组织中PTEN、MTA1 阳性表达均显著高于正常子宫内膜组织(P< 0.01)；PTEN 与MTA1 在子宫内膜癌组织中的表达呈负
相关( r=-0.35,P<0.05)。结论：PTEN 和MTA1 表达与子宫内膜癌的发生、发展及生物行为密切相关，且两者表达存在负相关性。 |
| 英文摘要: |
| Objective: To explore the expression of PTEN and MTA1 and their correlation in the endometrial cancer. Methods: In
130 cases of endometrial cancer and 40 cases of normal endometrial, the expression of PTEN and MTA1 was examined with immunohistochemistry
SP method and their correlation. Results: The expression of PTEN and MTA1 in endometrial cancer was higher than that in
normal endometrial. (P<0.01). PTEN expression levels in endometrial cancer were inversely correlated with MTA1 protein. (r= -0.35,
P<0.05). Conclusi |
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