| 贺安勇谢俊琴甘燕青谢丹杨卫.某三甲医院2007-2011 年ICU 气管切开术后肺部感染患者208 例
临床分析[J].现代生物医学进展英文版,2011,11(17):3329-3333. |
| 某三甲医院2007-2011 年ICU 气管切开术后肺部感染患者208 例
临床分析 |
| Pulmonary Infection after Tracheotomy in ICU of a First Class HospitalBetween 2007-2011：A Clinical Analysis of 208 Cases |
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| DOI： |
| 中文关键词: 肺部感染 气管切开 病原菌 重症监护病房 |
| 英文关键词: Lung infections Tracheal incision Pathogenic microorganism Intensive care unit |
| 基金项目: |
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| 中文摘要: |
| 助。方法：回顾性分析ICU 208 例气管切开术后并发肺部感染患者的痰细菌培养及药物敏感性测定结果。结果：共分离出420
株致病菌，革兰阴性菌293 株，占69.76％，其中铜绿假单胞菌98 株居首位；革兰阳性菌105 株，占25.24％，其中金黄色葡萄球菌
47 株为最多；真菌占22 株，占5.23％。分离出产超广谱β 内酰胺酶(ESBLs) 菌87 株，耐甲氧西林金黄色葡萄球菌(MRSA) 24
株。所分离致病菌对常用抗菌药物均有不同程度的耐药，且为多重耐药。结论：ICU 气管切开患者肺部感染病原菌以革兰阴性菌为
主，耐药率高，临床应加强病原学监测，重视细菌的种类分布和耐药趋势，合理使用抗生素。 |
| 英文摘要: |
| Objective: To investigate the types and drug resistance of pathogen of patients from intensive care unit (ICU) with lung
infections following tracheal incision, which is helpful for clinical therapy. Methods: 208 patients were complicated with lung infections
following tracheal incisions and a retrospective analysis of the bacteria isolates and their resistance to antibiotics was performed. Results:
Totally 420 strains of pathogens were isolated by bacterial culture. The Gram-negative bacteria (GNB) isolated were 293 strains
(69.76％), among which the Pseudomonas aeruginosa were 98 strains, which are contributed to the majority, the Gram-positive cocci
(GPC) were 105 strains (25.24％), and the staphylococcusaureus were the most ,47 strains. The fungi isolated were 22 strains, with a
proportion of 5.23%. The extended-spectrumβ-lactamases (ESBLs) isolatedwere 87 strains, andmethicillin-resistant staphylococcusaureus
(MRSA) were 24 strains. They were resistant to common antibiotics and particularly resistant to a multitude of antibiotics. Conclusions:
The major pathogenic microorganisms of the lung infections in patients after tracheal incision in ICU was GNB. The resistance rates to
antibiotics of the bacteria were very high. It is advisable that emphasis should be laid on the surveillance of bacterial resistance and
rational use of antimicrobial agents in clinical therapy. |
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