Article Summary
任建鸿郑文谢彦崔建涛1 宋玉琴李忠武2 时云飞2 林宁晶王小沛 涂梅峰应志涛平凌燕刘卫平邓丽娟张晨朱军.北京大学临床肿瘤学院、北京肿瘤医院暨北京市肿瘤防治研究所淋巴肿瘤科,恶性肿瘤 发病机制及转化研究教育部重点实验室,1 肿瘤分子生物学实验室,2 病理[J].现代生物医学进展英文版,2011,11(17):3275-3279.
北京大学临床肿瘤学院、北京肿瘤医院暨北京市肿瘤防治研究所淋巴肿瘤科,恶性肿瘤 发病机制及转化研究教育部重点实验室,1 肿瘤分子生物学实验室,2 病理
The Expression of Receptor Interaction Protein-3 in Lymphoma PatientsPathology Organization
  
DOI:
中文关键词: RIP3  淋巴瘤  病理  免疫组化
英文关键词: RIP3  Lymphoma  Pathology  Immunohistochemmistry
基金项目:
Author NameAffiliation
REN Jian-hong, ZHENG Wen, XIE Yan, CUN Jian-tao1, SONG Yu-qin, LI Zhong-wu2, SHI Yun-fei2, LIN Ning-jing, WANG Xiao-pei, TU Mei-feng, YING Zhi-tao, PING Ling-yan, LIU Wei-ping, DENG Li-juan, ZHANG Chen, ZHU Jun 北京大学临床肿瘤学院、北京肿瘤医院暨北京市肿瘤防治研究所淋巴肿瘤科恶性肿瘤 发病机制及转化研究教育部重点实验室1 肿瘤分子生物学实验室2 病理 
Hits: 848
Download times: 932
中文摘要:
      目的:探讨RIP3(受体相互作用蛋白-3)在淋巴瘤患者病理组织中是否表达及其亚细胞定位,并初步观察RIP3 的表达是否 与淋巴瘤病理恶性度相关。方法:(1) 利用免疫组化技术检测48 例淋巴瘤和非肿瘤侵润淋巴结病理组织中RIP3 表达,并观察 RIP3 亚细胞定位。结果:(1)RIP3 在淋巴瘤患者病理组织中均有表达,其亚细胞定位主要在细胞核,在细胞质中相对弱表达。(2) RIP3 表达与淋巴瘤病理恶性度可能存在相关性。结论:RIP3 在淋巴瘤患者病理组织中存在阳性表达,为研究RIP3 是否与淋巴瘤 的发病、临床表现和预后相关,提供了新的探索途径。
英文摘要:
      Objective: To investigate the expression of RIP3 (receptor interaction protein-3) in lymphoma patients pathological tissues and the sub-cellular localization, and to investigate the relationship of the expression of RIP3 and malignant degree of lymphoma. Methods: The RIP3 expression in 48 cases of the lymphoma and non-neoplastic lymph node pathological tissues was detected by immunohistochemmistry, and the sub-cellular localization of RIP3 was observed. Results: 1) There were RIP3 expresses in the lymphoma pathological tissues, which mainly located in nucleus but weekly in cytoplasm. 2) The expression of RIP3 had a relationship with malignant degrees of lymphoma. Conclusion: There was RIP3 expression in lymphoma pathological tissues, which shell new light to the study of mechanism of lymphoma.
View Full Text   View/Add Comment  Download reader
Close