| 赵亮1 曹红2.白芷有效成分提取工艺的优化及其中药材质量研究[J].现代生物医学进展英文版,2011,11(14):2759-2766. |
| 白芷有效成分提取工艺的优化及其中药材质量研究 |
| Optimization of Extraction Process of Active Ingredients from ChineseMedicine Angelica Dahurica and Its Quality Research |
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| DOI： |
| 中文关键词: 白芷 中药材 欧前胡素 提取工艺 药材质量 |
| 英文关键词: Angelica dahurica Chinese herbal medicine Imperatorin Extraction process Medicinal material quality |
| 基金项目: |
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| 中文摘要: |
| 目的：优化白芷中药材有效成分的提取工艺；全面系统地考察与研究市场上白芷中药材的质量。方法：以白芷中欧前胡素和
异欧前胡素的含量为指标，采用高效液相色谱法测定，利用正交试验，对渗漉法提取白芷有效成分的工艺条件进行优选；按照《中
国药典》2005 年版一部白芷项下[含量测定]方法检验了62 批次市场上销售的白芷药材中香豆素类物质的含量。结果：乙醇渗漉提
取法：药材浸泡24h，加80%乙醇8 倍量渗漉，欧前胡素和异欧前胡素的平均提取率为78%；市场上销售的白芷药材中香豆素类物
质的含量符合药典的要求。结论：应用渗漉法工艺提取白芷中药材有效成分效率高，稳定性好，适合工业化生产；目前市场上流通
的白芷中药材的质量可靠。 |
| 英文摘要: |
| Objective: To optimize the conditions for extracting effective components of Chinese herbal medicine Angelica
dahurica; to investigate and research on the quality of market herbal Angelica dahurica comprehensively and systematically. Methods:
Taking the content of imperatorin and iso imperatori for index, detect the effective components of angelica dahurica by high-performance
liquid chromatography (HPLC); using the orthogonal experiment, optimize the permeability technology conditions and extract the effective
ingredients of angelica dahurica; According to China pharmacopoeia 2005 version of angelica dahurica captioned [the content determination]
method, test the content of kind material coumarin of 62 batch market medicinal angelica dahurica. Results: Ethanol permeability
extraction: 24h, 80% medicinal soaking ethanol 8 times, the average extraction rate of imperatorin and iso impera- tori is 78%; the
content of coumarin in market medicinal Angelica dahurica conform to the pharmacopoeia requirements. Conclusion: The application of
permeability method extracting effective components of Angelica dahurica process of high efficiency, good stability, suitable for industrial
production; the quality of current market medicinal Angelica dahurica is reliable. |
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