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目的：观察2008 年1 月至2010 年12 月期间98 例TBSA 大于35％的烧伤病人创面联合应用磺胺嘧啶银混悬液联合银锌霜的疗效。方法：以同期76 例应用碘伏的病人作为对照，两组病人的平均年龄、烧伤面积、Ⅲ度面积无显著差别，用药方式均以半暴露为主。结果：磺胺嘧啶银混悬液联合银锌霜组能显著增加细菌转阴率，减少抗生素应用时间及植皮手术次数，缩短愈合时间。结论：磺胺嘧啶银混悬液联合银锌霜较碘伏能显著增加抗感染能力，有利于肉芽创面形成，为自行愈合或再次手术打下良好基础，值得应用。

英文摘要:

Objective: To evaluate the effect of combined suspl SD-Ag and SD-Ag-Zn-Azone cream on the wound healing in extensively burned patients. Methods: 174 burned patients admitted from January 2008 to December 2010, with burn size exceeding 35％ TBSA, were randomly allocated into two groups：combined suspl SD-Ag and SD-Ag-Zn-Azone cream group was applied in 98 patients; while in other 76 patients povidone-iodine was used as control. Results: There was no significant difference between the two groups in mean age, burn size, and treatment. Wound infections, days of antibiotics administration, times of grafting, healing times and degree of scar hyperplasia were remarkably reduced in combined suspl SD-Ag and SD-Ag-Zn-Azone cream group. Conclusion: Combination of SD-Ag Suspension with SD-Ag-Zn-Azone Cream in wound healing of extensively burned patients can significantly increase resistance to infection compared with Iodophor, which is suitable for topical use in the self-healing of extensively burned patients.

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