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目的：探讨注意缺陷多动障碍（ADHD）患儿睡眠障碍与血清铁蛋白水平的关系。方法：符合美国精神疾病诊断与统计手册第4 版（DSM-Ⅳ）中ADHD 诊断标准的62 例6-14 岁ADHD 患儿，由ADHD 患儿的父母填写睡眠障碍量表（SDSC），检测ADHD 患儿的血清铁蛋白水平。结果：与血清铁蛋白水平高于45μg/L 的ADHD 患儿相比较，血清铁蛋白水平低于45μg/L 的ADHD 患儿的SDSC“睡眠醒觉转换障碍”项评分和总分明显高于前者（P＜0.05)。2 组间其他项评分比较无显著性差异（P＞0.05)。SDSC “睡眠醒觉转换障碍”项评分与血清铁蛋白水平成负相关（P＜0.05)。结论：血清铁蛋白水平低于45μg/LADHD 患儿SDSC“睡眠醒觉转换障碍”（睡眠中的异常运动）的危险性显著增加。

英文摘要:

Objective: To assess the association between serum ferritin levels and parent reports of sleep disturbances in a sample of children with attention-deficit/hyperactivity disorder (ADHD). Methods: Sixty-two consecutively referred children (6-14 years) with ADHD diagnosed according to DSM-IV criteria. Parents filled out the Sleep Disturbance Scale for Children (SDSC) and serum ferritin levels were determined. Results: Compared to children with serum ferritin levels ≥45μg/L, those with serum ferritin levels ＜45μg/L had significantly higher scores on the SDSC subscale ''Sleep wake transition disorders'' (P＜0.05), as well as significantly higher scores on the total scores of SDSC. The mean scores on the other SDSC subscales did not significantly differ between children with serum ferritin ≥45 and ＜45μg/L. Serum ferritin levels were inversely correlated to SWTD scores (P＜0.05). Conclusions: Serum ferritin levels＜45μg/L might indicate a risk for sleep wake transition disorders, including abnormal sleep movements, in children with ADHD.

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