| 史艳明张弛△ 李华珠杨晓春周桂莲王敏熊璞王霞陈晶刘瑛.儿童与成人阻塞型睡眠呼吸暂停低通气综合征代谢
异常特征的比较[J].现代生物医学进展英文版,2011,11(10):1910-1912. |
| 儿童与成人阻塞型睡眠呼吸暂停低通气综合征代谢
异常特征的比较 |
| Metabolic Characteristics in Obstructive Sleep Apnea Syndrome betweenChildren and Adults |
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| DOI： |
| 中文关键词: 儿童 阻塞型睡眠呼吸暂停低通气综合征 呼吸暂停低通气指数 微觉醒指数 |
| 英文关键词: Children Obstructive sleep apnea syndrome Apnea-hypopnea index Arousal index |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨儿童及成人阻塞型睡眠呼吸暂停低通气综合症（OSAHS）发病原因、睡眠呼吸紊乱严重程度及合并代谢异常程度
的差别。方法：对我院2003 年1 月1 日至2010 年7 月1 日71 例诊断为OSAHS 住院患者进行回顾性调查，登记年龄、性别、发病
原因、血压、白细胞计数、中性粒细胞比率、淋巴细胞比率、呼吸暂停低通气指数（AHI）、夜间最低血氧饱和度、微觉醒指数。根据年
龄进行分组，年龄＜18 岁者为A 组，年龄≥18 岁者为B 组。比较两组发病原因、睡眠呼吸紊乱及合并代谢异常程度的差别。结果：
1.A 组慢性扁桃体炎和（或）腺样体肥大发生率明显高于B 组（P＜0.01），鼻中隔偏曲发生率明显低于B 组（P＜0.01）。2.与B 组比
较，A 组AHI 及微觉醒指数降低，夜间最低血氧饱和度升高（P＜0.01）；3.与B 组比较，A 组高血压、中性粒细胞比率、谷丙转氨酶
比例降低（P＜0.05）。结论：A 组睡眠呼吸紊乱程度及代谢异常较B 组程度轻，更需关注成人阻塞型睡眠呼吸暂停低通气综合症的
综合治疗。 |
| 英文摘要: |
| Objective: To investigate difference in metabolic parameters of children and adults with obstructive sleep apnea hypopnea
syndrome (OSAHS). Methods: The clinical data of 71 inpatients with OSAHS ,who were hospitalized in our hospital studied
retrospectively from January 2003 to July 2010, were studied retrospectively. The patients were divided into two groups according to age:
group A( < 18 years) and group B(≥18 years), comparing the etiology, sleep-disordered breathing and metabolic abnormalities between
the two groups. Results: 1. The prevelance of chronic tonsillitis and hypertrophy was significantly higher and the prevelance of septal
deviation was significantly lower in group A than in group B (P<0.01). 2. Compared with group B, the AHI and arousal index are
decreased in group A, while the lowest nocturnal oxygen saturation are increased (P<0.01); 3. The blood pressure, percentage of
neutrophils and alanine transaminase were higher in group B than in group A (P<0.05). Conclusion: Compared with children with
OSAHS, adults often show more severe sleep breathing disorders and combined with many metabolic abnormalities which should also be
awared. |
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