| 张凌段涛△.双胎输血综合征研究现状及新进展[J].现代生物医学进展英文版,2011,11(8):1586-1588. |
| 双胎输血综合征研究现状及新进展 |
| Current Status and Update on Twin-to-twin Transfusion Syndrome |
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| DOI： |
| 中文关键词: 胎盘间血管交通 单绒毛膜双胎 Quintero 分期 选择性激光凝结术 |
| 英文关键词: placental vascular connection monochorionic twin Quintero staging selective fetoscopic laser coagulation |
| 基金项目:上海市科委基础研究重点项目( 08JC1419800 |
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| 中文摘要: |
| 双胎输血综合征（twin-twin transfusion syndrome, TTTS）是单绒毛膜双胎最常见的一种并发症。TTTS 的发病机制尚不完全
明确，胎盘间存在血管交通是其发病的必要条件，但它难以解释胎儿所有的病理生理，而内分泌改变为TTTS 的发病机制提供了
一种可能的解释。TTTS 的临床诊断主要依靠超声。Quintero 分期是目前使用最广泛的分期标准，但其不能提供预测信息，存在一
定的局限性。治疗方面，选择性胎儿镜下激光消融术有着较好的胎儿存活率及神经系统预后，优于传统治疗方法，有较好的发展
前景。 |
| 英文摘要: |
| Twin-to-twin transfusion syndrome (TTTS) is the most common major complications in monochorionic pregnancy.
The onset of TTTS contribute to the role of placental vascular connection. But simple blood transfer from the donor to the recipient twin
cannot explain all of the pathological mechanism of TTTS. The endocrinology change may contribute a possible explanation. The
diagnosis of TTTS mainly depends on the ultrasound features. The widely used Quintero staging system in the estimation of twin-to-twin
transfusion syndrome is still controversial. The selective fetoscopic laser coagulation of anastomosing vessels is currently considered the
best modality and nervous system prognosis of treatment. |
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