| 魏薇1 周瑾2△ 刘莹1.人乳头瘤病毒(HPV)及其诱发子宫颈癌的新进展[J].现代生物医学进展英文版,2011,11(7):1385-1387. |
| 人乳头瘤病毒(HPV)及其诱发子宫颈癌的新进展 |
| New progress on Human Papilloma Virus Causing Cervical Cancer |
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| DOI： |
| 中文关键词: 人乳头瘤病毒 子宫颈癌 |
| 英文关键词: Human papilloma virus (HPV) cervical cancer |
| 基金项目: |
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| 中文摘要: |
| 子宫颈癌是一类发病率仅次于乳腺癌并严重危害女性生殖系统健康的最常见的妇科恶性肿瘤，在发展中国家，是女性癌症
死亡的第一因素。自德国科学家哈拉尔德·楚尔豪森(Harald zur Hausen)因发现人乳头瘤病毒(Human papillomavirus，HPV)导致子
宫颈癌而获得2008 年度的诺贝尔生理学或医学奖后，全世界广泛认可人乳头瘤病毒(HPV)是引起子宫颈癌的最主要生物学因
素。HPV 病毒的持续感染在子宫颈癌的发生、发展过程中起了重要作用。本文就HPV 病毒的生物学结构、女性生殖道HPV 病毒
的感染途径以及HPV 病毒诱发子宫颈癌机制的最近的研究进展进行扼要综述。 |
| 英文摘要: |
| Cervical cancer is a malignant tumor of gynecology, which seriously harm to women's reproductive system health, and
it's second only to breast cancer. In developing countries, cervical cancer is the first factor in female cancer deaths. Since The Nobel Prize
in Physiology or Medicine for 2008 has decided to award with a German scientist named Harald zur Hausen for his discovery of human
papilloma virus causing cervical cancer，throughout the world has recognized widely that human papilloma virus (HPV) was the most
important biological factors which caused cervical cancer. Persistent infection with HPV virus played an important role in the process of
cervical cancer occurred and development. In this Summary, I will outlines the recent progress including the biological structure of HPV
virus, the routes of female genital tract HPV virus infection and the mechanism of HPV viruses cause cervical cancer. |
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