| 胡明玉李倩章宏伟.红光促进难治性创面愈合的研究[J].现代生物医学进展英文版,2011,11(7):1346-1348. |
| 红光促进难治性创面愈合的研究 |
| Effect of Red LED Irradiation on Wound Healing |
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| DOI： |
| 中文关键词: 红光照射 难治性创面 VEGF 创面愈合 |
| 英文关键词: Red LED irradiation Refractory wounds VEGF Wound healing |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨红光照射对难治性创面的创缘组织中血管内皮细胞生长因子(vascular endothelial growth factor, VEGF)的表达及
治疗难治性创面的临床效果。方法：收集2008 年6 月-2010 年12 月因难治性创面入住笔者单位治疗的40 例患者，按治疗方法分
为红光照射治疗组20 例和常规治疗组20 例。常规治疗组患者创面以0.5%碘伏与水胶体敷料换药。治疗组在常规治疗的基础上
加用红光照射。于治疗后第7 天、14 天、21 天切取创缘组织，研究红光照射对创缘组织中VEGF 的影响，并比较两组患者的创面
愈合率和愈合时间。结果：临床实验中，治疗组创缘组织中的VEGF 含量明显高于对照组(P<0.01)；治疗组创面愈合率明显高于对
照组(P<0.01)；治疗组的愈合时间低于对照组(P<0.05)。结论：红光照射能显著提高创缘组织中VEGF 含量，减少创面愈合时间，促
进愈合。 |
| 英文摘要: |
| Objective: To study the effect of red LED irradiation on the vascular endothelial growth factor (VEGF) expression in
wounded tissue and its clinical effects. Methods: Immunohistochemical staining was used to detect the expression of VEGF in the
wounded tissue in different time, the rate of wound surface healing and time of wound healing were also observed. Results: VEGF was
expressed in the process of wound healing. The expression of VEGF in red LED irradiation group was higher than that in the control
group. Conclusion: red LED irradiation could increase the expression of VEGF in the wounded tissue and promote wound healing. |
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