| 于潇华郭小芳田智粟敏周锋刘立鹏.微核糖核酸在肿瘤血管生成中的调节作用[J].现代生物医学进展英文版,2011,11(6):1175-1177. |
| 微核糖核酸在肿瘤血管生成中的调节作用 |
| The regulation of microRNAs in tumor angiogenesis |
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| DOI： |
| 中文关键词: microRNAs 肿瘤血管生成 调节作用 |
| 英文关键词: microRNAs tumor angiogenesis regulation |
| 基金项目:湖南省自然科学基金资助项目（7JJ3058） |
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| 中文摘要: |
| 微核糖核酸( microRNAs, miRNAs ) 是广泛存在于真核生物中的一类短小的、不编码蛋白质的RNA 家族，由18-25 个核苷
酸组成的单链RNA。研究表明microRNAs 对肿瘤的发生发展具有重要的调节作用。肿瘤血管生成是实体瘤侵袭转移的关键步
骤，抗肿瘤血管生成的治疗已成为当前研究的焦点，已有研究表明，microRNAs 参与肿瘤血管生成的调节作用，通过对肿瘤血管
生成相关因子的调控，影响肿瘤生成。 |
| 英文摘要: |
| MicroRNAs (miRNAs) are an abundant class of small non-coding RNAs, which are single-stranded RNA of 18-25 nt.
Researches have showed that microRNAs has play an important role in regulating the tumorigenesis. Tumor angiogenesis is a key step in
invasion and metastasis of solid tumors, the current researches are going to focus on the anti-angiogenesis therapy. Studies have shown
that microRNAs involved in the regulation of tumor angiogenesis, which affect tumorigenesis by adjusting tumor angiogenesis factors.
Key words: microRNAs; tumor angiogenesis; regulation |
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