| 许宇静洪侃.胺碘酮致甲状腺功能异常的诊治进展[J].现代生物医学进展英文版,2011,11(5):968-971. |
| 胺碘酮致甲状腺功能异常的诊治进展 |
| The progress on the diagnosis and treatment of amiodarone-induced thyroiddysfunction |
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| DOI： |
| 中文关键词: 胺碘酮 甲状腺功能 诊断 治疗 |
| 英文关键词: Amiodarone thyroid function diagnosis treatment |
| 基金项目: |
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| 中文摘要: |
| 胺碘酮是治疗心律失常的常用药物。但由于其富含碘及自身固有的特性，可导致一系列甲状腺功能的紊乱，甚至引发明显
的甲状腺功能减退（甲减）或甲状腺功能亢进（甲亢）。对于胺碘酮所致甲减（AIH）的诊断和治疗目前比较清晰，但对胺碘酮所致甲
亢（AIT）的诊断、鉴别其亚型及治疗有一定的难度。 |
| 英文摘要: |
| Amiodarone is an effective medication approved for the treatment of cardiac arrhythmias. However, this drug has high
iodine content,and this feature plus the intrinsic effects on the body which make amiodarone toxic to the thyroid gland would induce a
series of disfunction，even result in overt hypothyroidism or thyrotoxicosis. So far,the diagnosis and treatment of amiodarone-induced
hypothyroidism(AIH) is clear and definite, whereas that of amiodarone-induced thyrotoxicosis(AIT) and the ability to distinguish between
the subtypes of the diease have much more challenge. And confirming the subtype of AIT is instructive to the treatment. |
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