| 高冰1 陶毅1 张宏亮1 苏政权2.载药纳米粒作为脑靶向给药系统的研究[J].现代生物医学进展英文版,2011,11(5):949-954. |
| 载药纳米粒作为脑靶向给药系统的研究 |
| 载药纳米粒作为脑靶向给药系统的研究 |
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| DOI： |
| 中文关键词: 血脑屏障 纳米粒 脑靶向 |
| 英文关键词: Blood-brain barrier Nanoparticles Brain targeting |
| 基金项目:广东省科技计划项目(2009B020313006)；广东省科技计划项目(2010B090400467)；
中山市科技计划项目(2009H017) |
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| 中文摘要: |
| 血脑屏障使大部分的活性药物很难由血液进入脑内发挥作用。载药纳米粒具有脑靶向性，可显著提高药物在脑内浓度，成
为药物突破血脑屏障的有效途径。本文综述了近年来载药纳米粒透过血脑屏障的研究进展,并对纳米粒载中药入脑提出展望。 |
| 英文摘要: |
| Most active drugs were kept from entering in the brain because of the blood-brain barrier (BBB). The drug loaded
nanoparticles have brain targeting quality so that the drugs' concentrations in brain could be outstandingly improved and it's becoming an
possible effective way to break through the difficult in drugs' permeation into BBB. This review summarizes the research progress of drug
loaded nanoparticles permeating the BBB and envisages the possibility of Chinese drugs loaded nanoparticles permeating the BBB. |
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