孙涛严金川陈小节梁仪赵建伟张朝普李璇.双核素心肌显像和门控心肌灌注显像检测糖尿病心肌病的临床应用[J].现代生物医学进展英文版,2011,11(1):87-89. |
双核素心肌显像和门控心肌灌注显像检测糖尿病心肌病的临床应用 |
18F-FDG/99m Tc-MIBI Dual-Isotope SPECT and Gated Myocardial Imagingfor Viability and Function Assessment of Diabetic Cardiomyopathy |
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DOI: |
中文关键词: 双核素同时采集 糖尿病心肌病 体层摄影术 发射型计算机 单光子 |
英文关键词: dual isotope simultaneous acquisition diabetic cardiomyopathy tomography emission-computed single-photon |
基金项目:江苏大学临床医学科技发展基金资助(JLY20080004) |
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中文摘要: |
目的:采用一日法静息99mTc- 甲氧基异丁基异腈(MIBI)及18 F- 脱氧葡萄糖(FDG)双核素同时采集(DISA)心肌灌注代谢显
像与门控心肌灌注显像,评价糖尿病心肌病(DCM)患者心肌灌注、存活和心功能状况。方法:36 例临床诊断为DCM 患者,进行
99mTc-MIBI 和18F-FDG DISA 灌注代谢显像及门控心肌灌注显像。结果:36 例DISA 显像中, 26 例为灌注/ 代谢不匹配型,提示
心肌存活,10 例为灌注代谢匹配型,提示心肌梗死,无存活心肌,心功能正常患者30 例。结论:一日法DISA 心肌灌注/ 代谢显像与
门控法心肌灌注显像,可全面评价糖尿病心肌病患者的心肌灌注、存活及心功能状况。 |
英文摘要: |
Objective: To investigate the diagnostic value of rest 99mTc-MIBI/18 F-FDG dual isotope simultaneous acquisition
(DISA) and gated myocardial imaging for viability and function assessment of patients with diabetic cardiomyopathy (DCM). Methods:
Thirty-six patients of diabetic cardiomyopathy performed 18 F-FDG/99m Tc-MIBI DISA SPECT and gated myocardial imaging. Results:
Among 36 DISA imagings, 26 cases were perfusion /metabolism mismatched and suggested viable myocardium,while 10 cases were perfusion
/metabolism matched suggesting myocardium infarction. Conclusion: The same-day protocol of DISA and gated myocardial imaging
study can well evaluate the myocardial viability and cardiac function for diabetic cardiomyopathy. |
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