| 陈瑞芳1 张挪富2 潘敏3 毛锐3 别英晖2 梁秋玲3.支气管哮喘急性发作期超敏C- 反应蛋白、白细胞、中性粒细胞比例检测
的意义及比较[J].现代生物医学进展英文版,2011,11(13):2540-2542. |
| 支气管哮喘急性发作期超敏C- 反应蛋白、白细胞、中性粒细胞比例检测
的意义及比较 |
| Clinical Significance of Detection of High Sensitivity C-reactive Protein,WBC,Neurocyte Percent in Serum in Acute Asthmatic Period |
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| DOI： |
| 中文关键词: 超敏C- 反应蛋白；白细胞计数 中性粒细胞比例；支气管哮喘；急性发作期 |
| 英文关键词: hs-CRP WBC Neurocyte percent Asthma |
| 基金项目: |
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| 中文摘要: |
| 目的：探讨超敏C- 反应蛋白（hs-CRP）、血白细胞总数（WBC）、中性粒细胞比例（N%）在支气管哮喘（简称哮喘）急性发作期
诊治中的临床意义。方法：分析60 例患者治疗前及自觉症状缓解时hs-CRP、WBC、N%动态变化情况，观察上述指标在急性发作
期的阳性率以及自觉症状缓解时的阴性率。结果：①hs-CRP、N%、WBC 在自觉症状缓解时均明显低于哮喘急性发作期( P < 0.
05); ②哮喘患者急性发作期hs-CRP、N%阳性率均高于WBC 阳性率, 且与后者比较均具有统计学差异( P < 0. 05);③哮喘患者经
治疗自觉症状缓解时hs-CRP、WBC 阴性率均高于N%阴性率, 且与后者比较均具有统计学差异( P < 0. 05)。结论：血清hs-CRP 既
可作为哮喘患者急性发作期感染的敏感指标，又是反映急性发作期治疗效果的早期评判指标, 比WBC、N%更迅速、敏感。 |
| 英文摘要: |
| Objective: To investigate the clinical significance of hs-CRP,WBC, Neurocyte Percent （N%）in the diagnosis and
treatment in acute asthmatic period. Methods: The changes of serum hs-CRP, WBC count, N% in 60 patients with asthma in acute
episode period before therapy and when feeling symptoms relief after therapy were retrospectively analyzed and summarized ;and their
positive rate in acute episode period and their negative rate when feeling symptoms relief was observed . Results: ① The levels of
hs-CRP,WBC count,N% in patients with asthma when feeling symptoms relief is obviously lower than that in acute episode period( P < 0.
05); ② The positive rate of hs-CRP and N% in patients with asthma in acute episode period is higher than that of WBC, and the
difference was obvious (P<0.05); ③ the negative rate of hs-CRP and WBC count in patients with asthma when feeling symptoms relief
after therapy is higher than that of N%, and the difference was obvious ( P<0.05); Conclusion: Serum hs-CRP can be as a sensitive index
in detecting the infection in patients with asthma in acute episode period, also be an index in early evaluating the therapeutic efficacy of
asthma in acute episode period, and is more sensitive and quicker compared with WBC,N%. |
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