董青川 王 禾 任 静2 宦 怡2 李 欣1.局限性前列腺癌病理分期比较的临床研究进展[J].现代生物医学进展英文版,2006,6(7):36-37. |
局限性前列腺癌病理分期比较的临床研究进展 |
The evaluation of clinic research to predicate the pathologicresult of organ- confined prostate cancer |
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DOI: |
中文关键词: 前列腺癌 临床分期 DCE- MRI 前列腺癌根治术 病理分期 |
英文关键词: Prostate cancer Clinical staging DCE- MRI Radical prostatectomy Pathological staging |
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中文摘要: |
目的: 探讨指诊分期和动态增强核磁( DCE- MRI) 分期预测局限性前列腺癌病理结果的临床价值。方法: 对42 例局
限性前列腺癌患者术前行经直肠指诊分期及MRI、DCE- MRI 分期, 并与根治术后的病理结果进行比较, 评价临床分期及DCEMRI
分期的临床意义。结果: DCE- MRI 分期与病理分期相比总体检测结果相同( 0. 25< P< 0. 5) , 能很好的预测前列腺内肿瘤的
病理分期; 直肠指诊诊断局限性前列腺癌有较高的敏感性( 89. 5%) , DCE- MRI 则有较高的特异性( 79. 17%) 及准确性( 83. 33%) 。
结论: 直肠指诊是筛查前列腺癌的重要手段, DCE- MRI 则能更好的了解肿瘤的范围及浸润情况, 更准确的预测肿瘤的病理分期。 |
英文摘要: |
Objective: To evaluate the clinical significance of clinical staging got by digital rectal examination ( DRE) and Dynamic
Contrast- enhancedMR Imaging ( DCE- MRI) staging for organ- confined prostate cancer before radical prostatectomy. Methods: To evaluate
the clinical significance of DRE and DCE- MRI, 42 patients with organ- confined prostate cancer were staged by DRE and DCE- MRI and
then contrasted to the pathological staging results. Results: contrasted with pathological staging there is no statistical significance ( 0. 25< P< 0.
5) in population, so we can consider that DCE- MRI staging can predict the pathological staging of organ- confined prostate cancer well. The
clinical staging was more sensitivity ( 89. 5%) than DCE- MRI staging, which is more specificity ( 79. 17%) and accuracy ( 83. 33%) in diagnosing
prostate cancer. Conclusion: Dig ital rectal examination is an important method to diagnosis prostate cancer and DCE- MRI can provide
us more information about carcinoma scope and infiltration so it can predict the pathological staging of organ- confined prostate cancer more precisely. |
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