| 刘 华 王 华 陈艳波 王洪云.慢性阻塞性肺疾病患者家庭长期氧疗的临床研究[J].现代生物医学进展英文版,2006,6(5):32-34. |
| 慢性阻塞性肺疾病患者家庭长期氧疗的临床研究 |
| Clinical research on domiciliary long- term oxygen therapy forpatients with chronic obstructive pulmonary disease |
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| DOI： |
| 中文关键词: 家庭长期氧疗 慢性阻塞性肺疾病 血气分析 肺功能 5 年生存率 |
| 英文关键词: Long- term oxygen therapy Chronic obstructive pulmonary disease( COPD) Arterial gas analysis Lung function Survival |
| 基金项目:Clinical research on domiciliary long- term oxygen therapy for
patients with chronic obstructive pulmonary disease |
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| 中文摘要: |
| 目的: 探讨家庭长期氧疗( LTOT) 对慢性阻塞性肺疾病( COPD) 患者的疗效。方法: 将我院同期住院病人随机分为
LTOT 组( 51 人) , 对照组( 52 人) 。全部病例在缓解期及治疗后每年测定PaO2、PaCO2、FVC、FEV1、HB、HCT 的数值及每年住院次数。
结果: 1 氧疗后1、2
、3
、4
、5
年与氧疗前比较, 低氧血症改善, FEV1 明显提高, HB、HCT 明显减少; 每年住院次数减少; o LTOT 组5
年生存率62. 75%, 对照组5 年生存率46. 15%, 差异有显著性( p< 0. 05) 。结论: 合理使用LTOT 对COPD 患者有良好的治疗作用,
可提高患者的5 年生存率。 |
| 英文摘要: |
| Objective: To observe the therapeutic effect of domiciliary long- term oxygen therapy ( LTOT) on patients with chronic
obstructive pulmonary disease( COPD) , with 5 - year- survival rate. Methods: The patients, who were admitted to hospital during the corresponding
period, were randomly divided into LTOT group ( n= 51) and control group( n= 52) . Values of PaO2, PaCO2, FVC, FEV1, HB and
HCT were examined at remission phase or annually after treatment, and admissions to emergency department were recorded. Results: ( 1) The
admissions to emergency department, dyspnea, hypoxemia, index of lung function and arterial gas analysis were greatly improved after LTOT. ( 2)
The 5- year survival rate ( 62. 75%) in LTOT group was significantly more than that in control group ( 46. 15%, p< 0. 05) . Conclusion: The
reasonable use of LTOT can achieve a good therapeutic effect on patients with COPD, which can improve their 5- year- survival rate. |
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