| 钟 萍1 蒋 毅2.A 型肉毒毒素治疗半侧面肌痉挛的临床疗效评价[J].现代生物医学进展英文版,2006,6(4):44-45. |
| A 型肉毒毒素治疗半侧面肌痉挛的临床疗效评价 |
| Clinical Analysis of Botulinus Toxin A for Hemifacial Spasm |
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| DOI： |
| 中文关键词: A 型肉毒毒素 面肌痉挛 抑郁 焦虑 |
| 英文关键词: Botulinus Toxin A (BTA) Hemifacial spasm Depression Anxiety |
| 基金项目: |
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| 中文摘要: |
| 目的:观察A 型肉毒毒素对面肌痉挛患者的痉挛程度、抑郁症状和焦虑症状的改善。方法:对58 例面肌痉挛患者进
行局部注射A 型肉毒毒素。在治疗前后对痉挛程度改善情况进行评定以及用汉密顿焦虑量表(HAMA)、汉密顿抑郁量表
(HAMD)对焦虑状态、抑郁状态进行评分, 并对药物的副作用进行观察。结果:A 型肉毒毒素明显改善面肌痉挛患者的痉挛程度,
治疗后2 周的HAMA、HAMD 评分较治疗前明显下降, 且差异具有统计学意义(P<0.01)。结论:局部注射A 型肉毒毒素可迅速缓
解或消除面肌痉挛患者肌肉痉挛及相关的抑郁和焦虑状态, 提高患者的生活质量。 |
| 英文摘要: |
| Objective :To observe the effect of Botulinum Toxin A (BTA)on the hemifacial spasm(HFS)patients with spasm , anxiety
and depression symptoms .Methods:58 patients with hemifacial spasm were treated with BTA.The degree of spasm alleviations and the
HAMA and HAMD of patients were assessed before and after treatment .Results :BTA can alleviate the spasm of all the patients.Two weeks after
treatment , the grades of HAMA and HAMD greatly decreased with statistic significance (P<0.01).Conclusion:BTA injected locally can
relieve the patients with HFS from spasm , anxiety and depression, and improve their living quality . |
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