| 卞艳萍.病毒性肝炎患者抗—HBcIgA 、IgE 、IgG 、IgM
平行检测的临床意义[J].现代生物医学进展英文版,2006,6(3):29-30. |
| 病毒性肝炎患者抗—HBcIgA 、IgE 、IgG 、IgM
平行检测的临床意义 |
| Parallel Examination of Anti -HBcIgA, IgE, IgG, and IgMof Patients with Virus Hepatitis |
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| DOI： |
| 中文关键词: 乙型肝炎 抗-HBcIgA、HBcIgE、HBcIgG、HbcIgM 平行检测 |
| 英文关键词: Virus hepatitis(VH) Parallel examination Hepatitis B virus(HBV) Anti - HBcIgA, HBcIgE , HBcIgG and HBcIgM |
| 基金项目: |
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| 中文摘要: |
| 目的:通过对乙肝病人血清抗-HBcIgA、HBcIgE、HbcIgG、HbcIgM 平行检测进一步地探讨其临床应用价值。方法:收集
216 份乙肝病人血清(均为我院住院病人的血清), 采用ELISA 法对病人血清抗-HBcIgA、HBcIgE 、HBcIgG、HBcIgM 平行检测, 并对
检测结果作统计学分析。结果:检测结果表明:抗-HBcIgA 是HBV 感染后肝脏损害的明显标志, 抗-HBcIgE 是HBV 感染后乙型
肝炎慢性化的标志, 抗-HBcIgG 持续存在则是以往感染的标志, 抗-HBcIgM 是HBV 感染后病毒持续复制的标志。结论:在急慢
性乙型肝炎、慢活肝与慢迁肝鉴别诊断中, 平行检测病人血清抗-HBcIgA、HBcIgE 、HbcIgG 、HbcIgM 对乙型肝炎慢性化及其预后估
价均有重要临床意义 |
| 英文摘要: |
| Objective :To further study the clinical application value of parallel examination of anti -HBcIgA, HBcIgE , HBcIgG
and HBcIgM in the sera of patients with hepatitis B(HB).Methods:216 blood specimens of HB patients, who were in-patients in our hospital
,were collected and examined .And the levels of anti -HBcIgA, HBcIgE , HBcIgG and HBcIgM in the sera of the patients were statistically
analysed.Results :The results showed that anti -HBcIgA was the identification marker of liver lesion post infection of HBV , anti-HBcIgE wa
the chronicity marker of HB post infection of HBV, anti -HBcIgG persistence existence was the infection marker in the past , and anti-HBcIgM
was the marker of virus persistence replication post infection of HBV.Conclusion:In the differential diagnosis of acute or chronic HB , chronic
active hepatitis and chronic persistent hepatitis, parallel examining anti -HBcIgA, HBcIgE, HBcIgG and HBcIgM in the sera of the patients will
be a significant means for HB chronicity and prognosis. |
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