| Objective: To compare the therapeutic effect of ureteroscopy (RIRS) combine with fine needle ultra fine channel percutaneous nephrolithotomy (SMP) and microchannel percutaneous nephrolithotomy (MPCNL) in the treatment of complex kidney stones. Method: Using random number table method, 100 patients with complex kidney stones who were admitted to our hospital from March 2022 to May 2024 were divided into control group of 50 cases and study group of 50 cases. The control group patients received MPCNL treatment, while the study group patients received fine needle SMP combined with RIRS treatment.The clinical indicators, pain status, inflammatory stress indicators, renal function indicators, and incidence of complications between the two groups were compared. Result: Surgical time in the study group was longer than that in the control group, the intraoperative blood loss was less than that of the control group, the postoperative hospitalization time and time to get out of bed after surgery were shorter than those in the control group (P<0.05). There was no statistically significant difference in the success rate of stone removal between the two groups (P>0.05). The visual analog pain scale (VAS) scores in the study group were lower than those in the control group at 6h, 24h, and 48h after surgery (P<0.05). Serum procalcitonin (PCT), high-sensitivity C-reactive protein (hs-CRP), cortisol(Cor), norepinephrine (NE), urea nitrogen (BUN), serum creatinine (Scr), and cystatin C (Cys C) in the study group were lower than those in the control group at 3d after surgery (P<0.05). There was no statistically significant difference in the incidence of complications between the two groups (P>0.05). Conclusion: Compared with MPCNL treatment for complex kidney stones, fine needle SMP combine with RIRS can reduce intraoperative bleeding, shorten time to get out of bed and hospitalization time, alleviate inflammatory stress response, and reduce damage to kidney function and postoperative pain without increasing the incidence of complications,. |
