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| 脉络膜厚度与原发性闭角型青光眼患者扫频OCT房角参数的相关性 |
| Correlation between choroidal thickness and sweep OCT angle parameters in patients with primary angle-closure glaucoma |
| 投稿时间：2025-03-15 修订日期：2025-03-15 |
| DOI： |
| 中文关键词: 脉络膜厚度 原发性闭角型青光眼 扫频OCT房角参数 |
| 英文关键词: Choroidal thickness Primary angle-closure glaucoma Sweep OCT angle parameters |
| 基金项目:赣州市科技计划项目（GZ2023ZSF454） |
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| 中文摘要: |
| 目的：观察脉络膜厚度与原发性闭角型青光眼（PACG）患者扫频OCT房角参数的相关性。方法：选择龙南市第一人民医院2022年6月~2024年8月期间收治的72例（144眼）PACG患者（PACG组），选取72例（144眼）同时期房角眼检查正常的志愿者（对照组）。对比两组眼球中心凹颞侧 2500 μm（T2.5）、眼球中心凹鼻颞侧 2500μm（N2.5）的脉络膜厚度及黄斑中心凹下脉络膜厚度（SFCT）。比较两组鼻侧、颞侧扫频OCT房角参数： 巩膜突角度（SSA500）、房角开放距离（AOD500）、房角隐窝面积（ARA500）、小梁网-虹膜间面积（TISA500）。采用Pearson分析脉络膜厚度与鼻侧、颞侧扫频OCT房角参数的相关性。结果：PACG组的T2.5、N2.5、SFCT脉络膜厚度厚于对照组（P<0.05）。PACG组鼻侧、颞侧AOD500、TISA500、SSA500、ARA500均低于对照组（P<0.05）。Pearson分析结果显示，T2.5、N2.5、SFCT与鼻侧、颞侧AOD500、TISA500、SSA500、ARA500呈负相关（P<0.05）。结论：PACG患者具有脉络膜厚、颞侧、鼻侧扫频OCT房角参数异常的特点，且脉络膜厚度与颞侧、鼻侧扫频OCT房角参数具有明显相关性。 |
| 英文摘要: |
| Objective: To investigate the correlation between choroidal thickness and sweep OCT angle parameters in primary angle-closure glaucoma (PACG) patients. Methods: 72 patients (144 eyes) with PACG who were admitted to First People''s Hospital of Longnan City from June 2022 to August 2024 (PACG group) were selected, and 72 volunteers (144 eyes) with normal periodic angle eye examination were selected (control group). The choroidal thickness of the foveo-temporal side of the eyeball 2500μm (T2.5), the foveo-naso-temporal side of the eyeball 2500μm (N2.5) and the choroidal thickness of the macular subfoveal (SFCT) were compared between the two groups, nasal and temporal scanning OCT angle parameters: scleral abruptness (SSA500), angle opening distance (AOD500), angle recess area (ARA500), trabecular meshwork iris area (TISA500) were compared between the two groups.The correlation between choroidal thickness and nasal and temporal scanning OCT angle parameters were analyzed by Pearson analysis. Results: The choroidal thickness of T2.5, N2.5 and SFCT in PACG group were thicker than those in control group (P<0.05). Nasal and temporal AOD500, TISA500, SSA500 and ARA500 in PACG group were lower than those in control group (P<0.05). Pearson analysis showed that T2.5, N2.5 and SFCT were negatively correlated with nasal and temporal AOD500, TISA500, SSA500 and ARA500 (P<0.05). Conclusion: Patients with PACG have thick choroid and abnormal parameters of temporal and nasal scan OCT, and there is a significant correlation between choroid thickness and temporal and nasal scan OCT parameters. |
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