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| 基于CT定位的火针取穴法治疗肺癌相关性咳嗽的临床研究 |
| Clinical Study on the Treatment of Lung Cancer-Related Cough by Fire Needle Acupuncture Selection Based on CT Localization |
| 投稿时间：2025-03-15 修订日期：2025-03-15 |
| DOI： |
| 中文关键词: CT定位 火针取穴 肺癌 咳嗽 临床疗效 |
| 英文关键词: CT localization Fire needle acupuncture selection Lung cancer Cough Clinical efficacy |
| 基金项目:福建中医药大学临床专项校管课题（XB2022068）；2022年度福建省中青年教师教育科研项目（科技类）（JAT220125） |
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| 中文摘要: |
| 目的：前瞻性分析评估基于CT定位的火针取穴法治疗肺癌相关性咳嗽的临床疗效。方法：前瞻性纳入福建中医药大学附属康复医院2020年1月到2023年12月期间接收的36名确诊为肺癌相关性咳嗽患者作为研究样本，按照随机数字表法分为对照组（18例）和观察组（18例），对照组采用常规病因治疗及对症处理，观察组在对照组基础上加用基于CT定位的火针取穴法治疗，疗程均为疗程28天。比较两组治疗28天后疗效改善率，治疗前及治疗28天后的视觉模拟评分（VAS）、中文版莱斯特咳嗽生命质量问卷（LCQ-MC）及外周血清细胞因子白细胞介素-6（IL-6）和白细胞介素-8（IL-8）水平。结果：治疗28天后，观察组患者的疗效改善率、VAS评分、LCQ-MC评分相较于对照组改善明显提升（P<0.05）；两组患者的IL-6及IL-8水平较治疗前均显著降低（P<0.05），但两组间的对比无统计学差异（P>0.05）。结论：结合CT精确定位引导下的火针取穴治疗能够显著提升肺癌相关咳嗽患者的治疗效果，有效减轻患者的咳嗽症状，提升患者的生活质量，缓解机体内的炎症反应。 |
| 英文摘要: |
| Objective:To prospectively analyze and evaluate the clinical efficacy of fire needle acupuncture selection based on CT localization in the treatment of lung cancer-related cough.Methods:A total of 36 patients with lung cancer-related cough who were admitted to the Rehabilitation Hospital Affiliated to Fujian University of Traditional Chinese Medicine from January 2020 to December 2023 were prospectively included as research samples.According to the random number table method,they were divided into control group (18 cases) and observation group (18 cases). The control group was treated with routine etiological treatment and symptomatic treatment, while the observation group was treated with fire needle acupuncture selection based on CT localization on the basis of the control group. The course of treatment was 28 days.The efficacy improvement rate after 28 days of treatment, visual analogue scale (VAS),leicester cough questionnaire in mandarin-Chinese(LCQ-MC) and levels of peripheral serum cytokines interleukin-6 (IL-6) and interleukin-8 (IL-8) before and after 28 days of treatment were compared between the two groups.Results: After 28 days of treatment, the efficacy improvement rate of curative effect,VAS score and LCQ-MC score in the observation group were significantly higher than those in the control group (P<0.05). The levels of IL-6 and IL-8 in the two groups were significantly lower than those before treatment (P<0.05),but there was no significant difference between the two groups (P>0.05).Conclusion:The treatment of fire needle acupuncture selection guided by CT localization can significantly improve the therapeutic effect of patients with lung cancer-related cough, effectively reduce the cough symptoms of patients, improve the quality of life of patients, and alleviate the inflammatory response in the body. |
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