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古方控涎丹抑制胰腺癌细胞增殖与迁移的机制研究 |
Study on the mechanism of inhibition of pancreatic cancer cell proliferation and migration by ancient prescription-controlled saliva Dan |
投稿时间:2025-02-25 修订日期:2025-02-25 |
DOI: |
中文关键词: 古方控涎丹 胰腺癌 NF-κB 信号通路 间皮素 |
英文关键词: Ancient prescription-controlled saliva Dan Pancreatic cancer NF-κB signaling pathway Mesothelin |
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中文摘要: |
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英文摘要: |
Objective: The aim of this study was to systematically investigate the effects of ancient prescription-controlled saliva Dan on the proliferation inhibition and migration ability of pancreatic cancer cell line PANC-1, and further reveal the potential mechanism of its role by inhibiting NF-κB signaling pathway and reducing the expression of mesothelin (MSLN), so as to provide a solid experimental basis for the application of traditional Chinese medicine in the treatment of pancreatic cancer. |
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