| 屈明利,史小莺,王 钱,徐慧双,王 云.血栓弹力图联合血浆t-PAIC、TAT在产后静脉血栓疾病中的表达意义
及其对疾病发生的影响[J].,2024,(23):4490-4492 |
| 血栓弹力图联合血浆t-PAIC、TAT在产后静脉血栓疾病中的表达意义
及其对疾病发生的影响 |
| The Expression Significance of ThromboelastographyCombined with Plasma t-PAIC and TAT in Postpartum VenousThrombotic Disease and Its Impact on Disease Occurrence |
| 投稿时间：2024-03-13 修订日期：2024-04-15 |
| DOI：10.13241/j.cnki.pmb.2024.23.023 |
| 中文关键词: 血栓弹力图 t-PAIC TAT 产后静脉血栓 |
| 英文关键词: Thromboelastography t-PAIC TAT Postpartum venous thrombosis |
| 基金项目:陕西省卫生健康委科研基金项目（2022A023） |
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| 中文摘要: |
| 摘要 目的：探讨血栓弹力图联合血浆t-PAIC、TAT在产后静脉血栓疾病中的表达意义及其对疾病发生的影响。方法：选取我院2019.1-2023.12共81例产后静脉血栓疾病患者为观察组，另选取同期81名产后未发生静脉血栓疾病的产妇作为对照组。对比两组相关指标，分析血栓弹力图、血浆t-PAIC、TAT对产后静脉血栓疾病的预测价值。结果：观察组生产后?琢值、Ma值高于对照组，Ly30值、R值、K值低于对照组（P＜0.05）；观察组孕早期及生产后t-PAIC、TAT水平高于对照组（P＜0.05）；血栓弹力图联合血浆t-PAIC、TAT的诊断灵敏度为71.57%，特异度为83.56%，联合诊断明显高于单一指标诊断（P＜0.05）；logistic回归分析结果表明：孕早期血栓弹力图中Ma值、t-PAIC、TAT对产后静脉血栓疾病具有独立预测价值（P＜0.05）。结论：血栓弹力图联合血浆t-PAIC、TAT对于产后静脉血栓疾病的预测与诊断具有重要价值，可考虑对孕妇孕早期、生产后进行检测从而对产后静脉血栓疾病的识别与判断提供参考意见。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the significance of thromboelastic gram combined with plasma t-PAIC and TAT in postpartum venous thrombosis disease and its influence on the occurrence of disease. Methods: A total of 81 patients with postpartum venous thrombosis disease in 2019.1-2023.12 in our hospital were selected as the observation group, and 81 women without postpartum venous thrombosis disease in the same period were selected as the control group. The predictive value of thromboelicogram, plasma t-PAIC, and TAT was analyzed. Results: The α and Ma values of the observation group were higher than the control group, Ly 30, R and K were lower than the control group (P<0.05); The level of t-PAIC and TAT in the early pregnancy and after production of the observation group was higher than that of the control group (P<0.05); The diagnostic sensitivity of thromboelastic gram combined with plasma t-PAIC, TAT was 71.57%, the specificity was 83.56%, the combined diagnosis was significantly higher than the single index diagnosis (P<0.05); The results of logistic regression analysis showed that Ma value, t-PAIC, and TAT in early pregnancy had independent predictive value for postpartum venous thrombosis disease (P<0.05). Conclusion: The combination of thromboelastography with plasma t-PAIC and TAT is of great value for the prediction and diagnosis of postpartum venous thrombosis diseases. It can be considered to test in early pregnancy and after childbirth to provide reference for the identification and judgment of postpartum venous thrombosis diseases. |
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