| 辛少伟,杨 阳,高 峰,孙 茜,刘海明,尚 进,刘 姣,叶长琦.38例肺癌的CT引导下微波消融安全性及初步疗效临床总结[J].,2024,(23):4444-4448 |
| 38例肺癌的CT引导下微波消融安全性及初步疗效临床总结 |
| Clinical Summary of Safety and Efficacy of CT-guided Microwave Ablation in 38 Cases of Lung Cancer |
| 投稿时间：2024-06-20 修订日期：2024-07-15 |
| DOI：10.13241/j.cnki.pmb.2024.23.009 |
| 中文关键词: 微波消融 肺癌 并发症 肺结节 |
| 英文关键词: Microwave ablation Lung cancer Complications Pulmonary nodule |
| 基金项目:联勤保障部队第九六二医院科研项目（962L202401） |
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| 中文摘要: |
| 摘要 目的：探讨CT引导下微波消融（microwave ablation，MWA）在肺癌治疗中的安全性及近期疗效。方法：选取2023年1月1日至2023年12月31日在联勤保障部队第九六二医院胸外科行CT引导下MWA治疗的38例肺癌患者病历资料，其中男性31例（81.6%），平均年龄44.2±14.3岁，肿瘤平均直径13.1±5.5mm，肿瘤位于右肺上叶9例（23.7%），右肺中叶7例（18.4%），右肺下叶6例（15.8%），左肺上叶10例（26.3%），左肺下叶6例（15.8%），回顾性分析临床资料、消融成功率、近期疗效及并发症情况，评价CT引导下微波消融在肺癌治疗中的安全性及有效性。结果：38例肺肿瘤共进行了38次消融治疗，均达到完全消融，消融成功率100%，术后平均随访10.2±2.9个月，随访期间无复发。影像学病灶转归为，纤维化29例（76.3%），病灶完全消失7例（18.4%），空洞2例（5.3%）。最常见的不良反应是疼痛，共有18例（47.4%）；最常见的并发症为气胸，38例患者中共出现12例（31.6%），其中11例为局限性气胸，仅需临床观察即可。仅出现1例严重并发症为大量气胸，经胸腔闭式引流治愈，无死亡病例。结论：CT引导下MWA是一种较有效的肺癌局部治疗手段，具有较好的安全性和一定疗效。 |
| 英文摘要: |
| ABSTRACT Objective: The purpose of this study was to investigate the safety and short-term efficacy of CT-guided microwave ablation (MWA) in the treatment of lung cancer. Methods: The data of 38 patients with lung cancer who underwent CT-guided MWA treatment in the Department of Thoracic Surgery of the 962 Hospital of the Joint Logistics Support Force from January 1, 2023 to December 31, 2023 were selected. Among them, 31 (81.6%) were males, with an average age of 44.2±14.3 years and an average tumor size of 13.1±5.5 mm. Tumors were located in the right upper lobe in 9 cases (23.7%), the right middle lobe in 7 cases (18.4%), the right lower lobe in 6 cases (15.8%), the left upper lobe in 10 cases (26.3%), and the left lower lobe in 6 cases (15.8%). The clinical data, complete ablation rate, short-term efficacy and complications were retrospectively analyzed to evaluate the safety and short-term efficacy of CT-guided MWA in the treatment of lung cancer. Results: A total of 38 pulmonary tumors were ablated for 38 times, all of which achieved complete ablation with a success rate of 100%. The average postoperative follow-up was 10.2±2.9 months, and there was no recurrence during the follow-up. The imaging outcomes was fibrosis in 29 cases (76.3%), complete disappearance in 7 cases (18.4%), and cavity in 2 cases (5.3%). The most common adverse reaction was pain (18 cases (47.4%). The most common complication was pneumothorax, which occurred in 12 of 38 patients (31.6%), of which 11 were localized pneumothorax, requiring only clinical observation. Only one serious complication was massive pneumothorax, which was cured by closed thoracic drainage, and no death occurred. Conclusion: CT-guided MWA is an effective local treatment for lung cancer with good safety and short-term efficacy. |
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