| 谷丽芳,拓新华,阎 樱,吕佳乐,党青华.肠道微生物制剂联合推拿疗法对肠易激综合征患儿的应用效果及对免疫功能、肠道菌群结构影响[J].,2024,(22):4361-4363 |
| 肠道微生物制剂联合推拿疗法对肠易激综合征患儿的应用效果及对免疫功能、肠道菌群结构影响 |
| The Application Effect of Gut Microbiota Preparation Combined with Massage Therapy on Children with Irritable Bowel Syndrome and Its Impact on Immune Function and Gut Microbiota Structure |
| 投稿时间：2024-07-10 修订日期：2024-08-15 |
| DOI：10.13241/j.cnki.pmb.2024.22.048 |
| 中文关键词: 肠道微生物制剂 推拿疗法 肠易激综合征 |
| 英文关键词: Intestinal microbiota preparations Tuina therapy Irritable bowel syndrome |
| 基金项目:2020年度陕西省社科基金项目(2020P025) |
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| 中文摘要: |
| 摘要 目的：探讨肠道微生物制剂联合推拿疗法对肠易激综合征患儿的应用效果及对免疫功能、肠道菌群结构影响。方法：选取我院2021.1-2024.1收治的90例肠道易激综合征患儿，分为联合组与对照组，各45例。对照组患儿采取常规对症治疗，联合组患儿在对照组基础上增加肠道微生物制剂联合推拿疗法。对比两组相关指标。结果：联合组总有效率高于对照组（P＜0.05）；联合组治疗后CD4+水平、CD3+、CD4+/CD8+高于对照组，两组治疗后高于治疗前（P＜0.05）；联合组治疗后MAST、DDT、AC、MIC高于对照组，两组治疗后高于治疗前，RRP低于对照组，两组治疗后低于治疗前（P＜0.05）；联合组治疗后乳酸杆菌数量、双歧杆菌、类杆菌高于对照组，且两组治疗后高于治疗前，大肠杆菌、粪肠球菌低于对照组，且两组治疗后低于治疗前（P＜0.05）。结论：针对肠易激综合征患儿采取肠道微生物制剂联合推拿疗法可提升其临床疗效，提高免疫功能与肠运动功能，改善肠道菌群结构。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the application effect of gut microbiota preparation combined with massage therapy on children with irritable bowel syndrome, as well as its impact on immune function and gut microbiota structure. Methods: 90 children with irritable bowel syndrome admitted to 2021.1-2024.1 in our hospital were divided into combined group and control group, 45 cases each. The children in the control group adopted routine symptomatic treatment, and the combined group added intestinal microbial preparations and combined massage therapy on the basis of the control group. Compare the two groups of related indicators. Results: The total response rate in the combination group was higher than that in the control group(P<0.05); After treatment, CD4+ levels, CD3+, and CD4+/CD8+ were higher in the combination group than in the control group, Both groups were higher than before treatment(P<0.05); MAST, DDT, AC and MIC were higher than the control group, Both groups were higher after treatment than before treatment, The RRP was lower than that in the control group, After treatment was lower than before treatment(P<0.05); The number of Lactobacillus, bifidobacterium and Bacilloids were higher in the combination group than in the control group, And higher after treatment than before treatment, E. coli, Enterococcus faecalis were lower than the control group, After treatment was lower than before treatment (P<0.05). Conclusion: The combination of gut microbiota preparations and massage therapy can improve the clinical efficacy, immune and intestinal motility functions, and improve the structure of gut microbiota in children with irritable bowel syndrome. |
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