| 李积安,胡 蕤,马 磊,王程阳,钟勇进.FAR、SII及Caprini评分与老年肺癌患者术后下肢深静脉血栓形成的关系及风险预警模型构建[J].,2024,(22):4351-4354 |
| FAR、SII及Caprini评分与老年肺癌患者术后下肢深静脉血栓形成的关系及风险预警模型构建 |
| Relationship between FAR, SII and Caprini Score and Postoperative Deep Venous Thrombosis of Lower Extremity in Elderly Patients with Lung Cancer and Construction of a Risk Warning Model |
| 投稿时间：2024-06-18 修订日期：2024-07-10 |
| DOI：10.13241/j.cnki.pmb.2024.22.045 |
| 中文关键词: 老年 肺癌 FAR SII Caprini评分 下肢深静脉血栓形成 列线图 |
| 英文关键词: Elderly Lung cancer FAR SII Caprini score Deep venous thrombosis of lower extremity Nomogram |
| 基金项目:陕西省创新能力支撑计划项目（2018KJXX-092） |
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| 中文摘要: |
| 摘要 目的：探讨纤维蛋白原/白蛋白比值（FAR）、系统免疫炎症指数（SII）及Caprini评分与老年肺癌患者术后下肢深静脉血栓形成（DVT）的关系，并构建列线图风险预警模型。方法：根据352例老年肺癌患者术后是否发生下肢DVT将其分为发生组（84例）和未发生组（268例）。检测患者术后1 d的FAR、SII和Caprini评分。Logistic回归分析老年肺癌患者术后下肢DVT的影响因素，并构建列线图风险预警模型。结果：合并糖尿病、高脂血症、术前化疗、术后卧床时间延长、FAR、SII、Caprini评分均升高为老年肺癌患者术后下肢DVT的独立危险因素（P＜0.05）。列线图风险预警模型的预测曲线与理想曲线贴合度良好，且H-L检验P＞0.05。结论：FAR、SII及Caprini评分均升高为老年肺癌患者术后下肢DVT的独立危险因素，构建的列线图风险预警模型对老年肺癌患者术后下肢DVT具有较高的预测价值。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the relationship between fibrinogen/albumin ratio (FAR), systemic immune inflammation index (SII) and Caprini score and postoperative deep venous thrombosis (DVT) of lower extremity in elderly patients with lung cancer, and to construct a nomogram risk warning model. Methods: According to whether the lower extremity DVT occurred in 352 elderly patients with lung cancer after operation, they were divided into occurrence group (84 cases) and non-occurrence group (268 cases). The FAR, SII and Caprini score of the patients at 1 day after operation were detected. The influencing factors of postoperative lower extremity DVT in elderly patients with lung cancer were analyzed by Logistic regression, and build a nomogram risk warning model. Results: Combined diabetes mellitus, hyperlipidemia, preoperative chemotherapy, prolonged postoperative bed duration, and increased FAR, SII, and Caprini score were independent risk factors for postoperative lower extremity DVT in elderly patients with lung cancer(P<0.05). The prediction curve of the nomogram risk early warning model was in good agreement with the ideal curve, and the H-L test P>0.05. Conclusion: The increase of FAR, SII and Caprini score are independent risk factors for postoperative lower extremity DVT in elderly patients with lung cancer, and construction of nomogram risk warning model has a high predictive value for postoperative lower extremity DVT in elderly patients with lung cancer. |
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