| 黄娜娟,李维娜,陈吉婷,赖钟祺,杜亚茹.25G+微创玻璃体切割术联合雷珠单抗治疗玻璃体视网膜疾病效果分析[J].,2024,(21):4161-4163 |
| 25G+微创玻璃体切割术联合雷珠单抗治疗玻璃体视网膜疾病效果分析 |
| Analysis of the Effect of 25G+Minimally Invasive Vitrectomy Combined with Ranibizumab in the Treatment of Vitreoretinal Diseases |
| 投稿时间：2024-06-20 修订日期：2024-07-15 |
| DOI：10.13241/j.cnki.pmb.2024.21.033 |
| 中文关键词: 增生性玻璃体视网膜病变 玻璃体切割术 雷珠单抗 |
| 英文关键词: Proliferative vitreoretinopathy Vitrectomy Ranibizumab |
| 基金项目:福建省自然科学基金项目（2023J01241） |
|
| 摘要点击次数: 38 |
| 全文下载次数: 15 |
| 中文摘要: |
| 摘要 目的：探究25G+微创玻璃体切割术联合雷珠单抗治疗玻璃体视网膜疾病效果。方法：选取我院2022.1-2024.1收治的80例增生性玻璃体视网膜病变（PVR）患者，分为对照组39例和观察组41例。对照组采用25G+微创玻璃体切割术治疗，观察组在对照组基础上使用玻璃体腔内注射雷珠单抗。比较两组各项指标及并发症发生率。结果：观察组手术时间、水肿、出血、渗出吸收时间均短于对照组，术中出血量少于对照组（P<0.05）；术后观察组视力高于对照组，黄斑中央凹陷厚度、眼压低于对照组（P<0.05）；观察组房水IFN-γ、IL-6、IL-10水平低于对照组（P<0.05）；观察组并发症发生率低于对照组（P<0.05）。结论：PVR患者应用25G+微创玻璃体切割术联合雷珠单抗可有效缩短手术时间，改善视力，抑制炎症反应，降低并发症发生率。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of 25G+ minimally invasive vitrectomy combined with ranibizumab in the treatment of vitreoretinal diseases. Methods: A total of 80 patients with hyperplastic vitreoretinopathy (PVR) admitted to 2022.1-2024.1 in our hospital were divided into 39 patients in the control group and 41 patients in the observation group. The control group was treated with 25G+minimally invasive vitrectomy, and the observation group used intravitreal injection of ranizzumab based on the control group. The various indexes and complication rates were compared between the two groups. Results: The operation time, edema, bleeding, and absorption time were shorter than the control group, and the intraoperative bleeding volume was less than the control group (P<0.05); the postoperative visual acuity was higher than the control group, the central macular thickness and intraocular pressure were lower than the control group (P<0.05); the aqueous IFN-γ, IL-6, and IL-10 were lower than the control group (P<0.05); the complication rate was lower than the control group (P<0.05). Conclusion: The application of 25G+minimally invasive vitrectomy combined with ranibizumab in PVR patients can effectively shorten the surgical time, improve vision, inhibit inflammatory reactions, and reduce the incidence of complications. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
