| 黄鸿艳,王新雨,包春凤,黄丽雪,王大庆,沈志斌.FS-LASIK围术期应用0.05%环孢素滴眼液（Ⅱ）对术后干眼症状
及泪膜稳定性的影响[J].,2024,(20):3974-3976 |
| FS-LASIK围术期应用0.05%环孢素滴眼液（Ⅱ）对术后干眼症状
及泪膜稳定性的影响 |
| Effect of 0.05% Cyclosporine Eye Drops (II) on Dry Eye Symptomsand Tear Film Stability after FS-LASIK |
| 投稿时间：2024-05-24 修订日期：2024-06-15 |
| DOI：10.13241/j.cnki.pmb.2024.20.048 |
| 中文关键词: 飞秒激光辅助准分子激光原位角膜磨镶术 环孢素滴眼液 干眼症状 泪膜稳定性 |
| 英文关键词: Femtosecond laser-assisted laser in situ keratomileusisis Cyclosporine eye drops Dry eye symptoms Tear film stability |
| 基金项目:四川省科技厅面上项目（2018JY0388） |
|
| 摘要点击次数: 23 |
| 全文下载次数: 16 |
| 中文摘要: |
| 摘要 目的：观察飞秒激光辅助准分子激光原位角膜磨镶术（FS-LASIK）围术期应用0.05%环孢素（CsA）滴眼液（Ⅱ）对术后干眼症状及泪膜稳定性的影响。方法：92例行FS-LASIK手术且术后出现干眼症状的患者分为术前使用0.05%CsA滴眼液（Ⅱ）组（A组）36例、术后1周开始使用0.05%CsA滴眼液（Ⅱ）组（B组）32例、不使用0.05%CsA滴眼液（Ⅱ）组（C组）24例。对比三组中国干眼问卷评分、泪膜破裂时间（BUT）、角膜荧光素染色（FL）、结膜丽丝胺绿染色（LG）、泪液分泌试验（SIt）。结果：B组、C组术后1周、1个月及3个月中国干眼问卷评分、FL、LG高于A组，且C组高于B组（P<0.05）。B组、C组术后1周、1个月及3个月BUT、SIt低于A组，且C组低于B组（P<0.05）。结论：FS-LASIK术前使用0.05%CsA滴眼液（Ⅱ）可以有效缓解患者术后干眼症状，提高泪膜稳定性。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effect of perioperative application of 0.05% cyclosporine (CsA) eye drops (II) on dry eye symptoms and tear film stability after femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). Methods: 92 patients who underwent FS-LASIK surgery and had dry eye symptoms after surgery were divided into 36 patients who used 0.05% CsA eye drops before operation (group A), 32 patients who used 0.05 % CsA eye drops 1 week after operation (group B), and 24 patients who did not use 0.05% CsA eye drops (group C). The Chinese dry eye questionnaire score, tear film rupture time (BUT), corneal fluorescein staining (FL), conjunctival lissamine green staining (LG), and tear secretion test (SIt) were compared among three groups. Results: The Chinese dry eye questionnaire score, FL and LG in group B and group C were higher than those in group A at 1 week, 1 month and 3 months after operation, and those in group C were higher than those in group B (P<0.05). BUT and SIt in group B and group C were lower than those in group A at 1 week, 1 month and 3 months after operation, and those in group C were lower than those in group B (P<0.05). Conclusion: The use of 0.05% CsA eye drops (II) before FS-LASIK can effectively alleviate the symptoms of dry eye, and improve the stability of tear film. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
