| 范晓娟,杨 浩,刘柯君,赖榆芳,刘 婷.抑木扶土针刺疗法联合腹部推拿对肝郁脾虚型功能性消化不良患者胃肠激素和肠道菌群的影响[J].,2024,(15):2878-2881 |
| 抑木扶土针刺疗法联合腹部推拿对肝郁脾虚型功能性消化不良患者胃肠激素和肠道菌群的影响 |
| Effects of Yimufutu Acupuncture Therapy Combined with Abdominal Massage on Gastrointestinal Hormones and Intestinal Microflora in Patients with Functional Dyspepsia of Liver Depression and Spleen Deficiency Type |
| 投稿时间：2024-01-27 修订日期：2024-02-22 |
| DOI：10.13241/j.cnki.pmb.2024.15.013 |
| 中文关键词: 抑木扶土针刺疗法 腹部推拿 肝郁脾虚型 功能性消化不良 胃肠激素 肠道菌群 |
| 英文关键词: Yimufutu acupuncture therapy Abdominal massage Liver depression and spleen deficiency type Functional dyspepsia Gastrointestinal hormones Intestinal microbiota |
| 基金项目:广东省中医药局科研项目（20181078） |
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| 中文摘要: |
| 摘要 目的：观察抑木扶土针刺疗法联合腹部推拿对肝郁脾虚型功能性消化不良（FD）患者胃肠激素和肠道菌群的影响。方法：按照随机数字表法将江门市妇幼保健院2020年8月~2022年12月期间收治的120例肝郁脾虚型FD患者分为对照组（60例，西药治疗基础上结合腹部推拿）和观察组（60例，对照组的基础上接受抑木扶土针刺疗法）。对比两组疗效、中医症候积分、胃肠激素和肠道菌群。结果：与对照组相比，观察组的临床总有效率更高（P<0.05）。与对照组治疗2个疗程后相比，观察组主症、次症、总分更低（P<0.05）。治疗两个疗程后，观察组生长抑素、胃泌素低于对照组，胃动素高于对照组（P<0.05）。治疗两个疗程后，观察组双歧杆菌、乳杆菌水平高于对照组，酵母菌、肠杆菌、肠球菌水平低于对照组（P<0.05）。结论：抑木扶土针刺疗法联合腹部推拿治疗肝郁脾虚型FD患者，可调节胃肠激素和肠道菌群，改善临床症状。 |
| 英文摘要: |
| ABSTRACT Objective: To observe the effects of Yimufutu acupuncture therapy combined with abdominal massage on gastrointestinal hormones and intestinal microflora in patients with functional dyspepsia (FD) of liver depression and spleen deficiency type. Methods: 120 FD patients with liver depression and spleen deficiency type admitted to Jiangmen Maternal and Child Health Hospital from August 2020 to December 2022 were divided into control group (60 cases, combine with abdominal massage on the basis of western medicine treatment) and observation group (60 cases, treated with Yimufutu acupuncture therapy on the basis of control group) according to the random number table method. The curative effect, traditional chinese medicine syndrome score, gastrointestinal hormones and intestinal microflora were compared between two groups. Results: Compared with control group, the total clinical effective rate in observation group was higher (P<0.05). Compared with control group, 2 courses after treatment, the main symptoms, secondary symptoms and total scores in observation group were lower (P<0.05). 2 courses after treatment, somatostatin and gastrin in observation group were lower than those in control group, and motilin was higher than that in control group (P<0.05). 2 courses after treatment, the levels of bifidobacterium and lactobacillus in observation group were higher than those in control group, and the levels of yeast, enterobacter and enterococcus were lower than those in control group (P<0.05). Conclusion: Yimufutu acupuncture therapy combined with abdominal massage in the treatment of FD patients with liver depression and spleen deficiency type, which can regulate gastrointestinal hormones and intestinal microbiota, and improve clinical symptoms. |
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