| Objective: To investigate the influencing factors of intestinal fistula after intestinal resection of ovarian cancer cytoreductive surgery. Methods: 89 patients who underwent ovarian cancer cytoreductive surgery for intestinal resection in our hospital from January 2021 to June 2023 were included. patients were divided into intestinal fistula group (n=16) and non-intestinal fistula group (n=73) according to whether postoperative intestinal fistula. The influencing factors of intestinal fistula occurred after intestinal resection in ovarian cancer undergoing cytoreductive surgery patients were analyzed by univariate and multivariate Logistic regression models. The predictive value of influencing factors for intestinal fistula after intestinal resection in ovarian cancer undergoing cytoreductive surgery patients were analyzed by receiver operating characteristic (ROC) curve. Results: There were 16 cases intestinal fistula in 89 patients undergoing ovarian cancer cytoreductive surgery for intestinal resection, and the incidence of intestinal fistula was 17.98%. Univariate analysis showed that, There were significant differences in body mass index (BMI), preoperative carbohydrate antigen?125 (CA125), ascites volume, surgical complexity score, preoperative albumin, and intraoperative blood loss between intestinal fistula group and non-intestinal fistula group (P<0.05), There was no significant difference in age, preoperative comorbidities, pathological type, International Federation of Gynecology and Obstetrics (FIGO) stage, pathological grade, operation time, anastomosis method and number of resected intestinal segments (P>0.05). BMI≥24kg/m2, elevated preoperative CA125, ascites volume, surgical complexity score, and intraoperative blood loss were independent risk factors for affecting intestinal fistula after intestinal resection in ovarian cancer cytoreductive surgery patients (P<0.05). And elevated preoperative albumin was a protective factor (P<0.05). The results of ROC analysis showed that, the area under the curve (AUC) of BMI, preoperative albumin, preoperative CA125, ascites volume, intraoperative blood loss, and surgical complexity score were 0.637, 0.628, 0.610, 0.697, 0.772, and 0.649, respectively. The AUC predicted by the combined detection of the above indicators was 0.902, suggesting that the predictive efficacy of combined detection was better than that of single indicator. Conclusion: BMI ≥24kg/m2, elevated preoperative CA125, elevated ascites volume, elevated intraoperative blood loss, and elevated surgical complexity score are independent risk factors for intestinal fistula after enterectomy for ovarian cancer, And elevated preoperative albumin was a protective factor. the combined detection of the above indicators has a certain predictive value for intestinal fistula after intestinal resection of ovarian cancer cytoreductive surgery. |
