| 杨 柳,和娇娇,蒋 琪,党彩虹,李维辛.住院老年人骨骼肌质量指数与TG/HDL-C的相关性研究[J].,2024,(9):1796-1800 |
| 住院老年人骨骼肌质量指数与TG/HDL-C的相关性研究 |
| Correlation between Skeletal Muscle Mass Index and TG/HDL-C in Hospitalized Elderly |
| 投稿时间：2023-11-10 修订日期：2023-12-31 |
| DOI：10.13241/j.cnki.pmb.2024.09.039 |
| 中文关键词: 骨骼肌质量指数 肌少症 甘油三酯与高密度脂蛋白胆固醇比值 血脂 |
| 英文关键词: Skeletal muscle mass index Sarcopenia TG/HDL-C Blood fat |
| 基金项目:甘肃省自然科学基金项目（22JR5RA925） |
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| 中文摘要: |
| 摘要 目的：分析住院老年人骨骼肌质量指数（ASMI）与甘油三酯与高密度脂蛋白胆固醇比值（TG/HDL-C）的相关性，评估TG/HDL-C对老年住院患者发生低ASMI的预测价值。方法：选取2022年7月至2023年8月兰州大学第一医院收治的299例住院老年患者，根据2019年亚洲肌少症工作组发布的关于肌少症的诊疗共识，分为低ASMI组（105例）和正常ASMI组（194例）。比较2组的临床资料，通过Spearman相关分析研究ASMI与相关变量之间的相关性，通过多因素Logistic回归分析ASMI的影响因素，采用受试者工作特征（ROC）曲线评估TG/HDL-C对老年住院患者发生低ASMI的预测价值。结果：随着ASMI的增加，TG/HDL-C比值增加（P＜0.001）。Spearman相关分析显示，ASMI与腰臀比、基础代谢、肌肉、握力、体脂率、BMI、ALT、TG、TG/HDL-C均成正相关（P＜0.05），与HDL-C成负相关（P＜0.05）。 多因素分析显示：体脂率、尿酸、TG/HDL-C是ASMI的独立影响因素。ROC曲线显示，TG/HDL-C曲线下面积为0.67（95%CI：0.607~0.722）。结论：高TG/HDL-C是低ASMI的保护因素。TG/HDL-C对低ASMI的发生有一定的预测价值，通过简单易得的血脂指标来估计骨骼肌质量易于实现，对可疑早期肌少症患者进行监测与干预。 |
| 英文摘要: |
| ABSTRACT Objective: To analyze the correlation between skeletal muscle mass index (ASMI) and TG/HDL-C in hospitalized elderly patients. To evaluate the predictive value of TG/HDL-C for low ASMI in elderly hospitalized patients. Methods: A total of 299 hospitalized elderly patients admitted to the First Hospital of Lanzhou University from July 2022 to August 2023 were selected and divided into low ASMI group (105 cases) and normal ASMI group (194 cases) according to the consensus on the diagnosis and treatment of sarcopenia issued by the Asian Working Group on sarcopenia in 2019. Clinical data of the two groups were compared, Spearman correlation analysis was used to study the correlation between ASMI and related variables, and multi-factor Logistic regression was used to analyze the influencing factors of ASMI. the predictive value of TG/HDL-C in the occurrence of low ASMI in elderly hospitalized patients was evaluate by receiver operating characteristic (ROC) curve. Results: With the increase of ASMI, TG/HDL-C ratio increased (P<0.001). Spearman correlation analysis showed that ASMI was positively correlated with waist-to-hip ratio, basal metabolism, muscle, grip strength, body fat percentage, BMI, ALT, TG, TG/HDL-C, and negatively correlated with HDL-C (P<0.05). Multifactor analysis showed that body fat percentage, uric acid and TG/HDL-C were independent influencing factors of ASMI. ROC curve showed that the area under TG/HDL-C curve was 0.67 (95% CI: 0.607~0.722). Conclusion: High TG/HDL-C was protective factors for low ASMI. TG/HDL-C has certain predictive value for the occurrence of low ASMI, and it is easy to estimate skeletal muscle mass by simple and easily obtained lipid indexes, so early monitoring and intervention can be carried out for patients with suspected sarcopenia. |
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