| 刘建梁,王 苗,景福权,赵 平,周 钰.针灸联合手法推拿对腰椎间盘突出症的应用效果及血浆β-内啡肽及腰椎功能的影响[J].,2023,(20):3869-3873 |
| 针灸联合手法推拿对腰椎间盘突出症的应用效果及血浆β-内啡肽及腰椎功能的影响 |
| The Effect of Acupuncture Combined with Manipulation on Lumbar Disc Herniation and the Effects of Plasma β-endorphin and Lumbar Function |
| 投稿时间：2023-03-06 修订日期：2023-03-30 |
| DOI：10.13241/j.cnki.pmb.2023.20.014 |
| 中文关键词: 针灸 手法推拿 腰椎间盘突出症 血浆β-内啡肽 腰椎功能 |
| 英文关键词: Acupuncture and moxibustion Manual massage Lumbar disc herniation Plasma β- Endorphin Lumbar function |
| 基金项目:新疆维吾尔自治区自然科学基金项目（2021D01C349） |
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| 中文摘要: |
| 摘要 目的：探讨针灸联合手法推拿对腰椎间盘突出症的应用效果及血浆β-内啡肽（β-EP）及腰椎功能的影响。方法：选取我院2020年1月到2022年12月收治的102例腰椎间盘突出症患者作为研究对象，随机分为A（n=35）、B（n=35）、C（n=32）三组。A组患者采取针灸治疗，B组患者采取手法推拿治疗，C组患者采取针灸联合手法推拿治疗，对比三组患者临床疗效，治疗前与治疗1个月后的血清炎症因子及血浆β-内啡肽表达水平，疼痛水平以及腰椎功能情况。结果：C组治疗总有效率明显高于A组和B组（P＜0.05），但A组与B组对比无明显差异（P＞0.05）；三组患者治疗前肿瘤坏死因子-α（TNF-α）、基质金属蛋白酶-3（MMP-3）、白细胞介素-1β（IL-1β）、β-EP对比无差异（P＞0.05），治疗后三组患者TNF-α、MMP-3、IL-1β水平均降低，且C组低于A组与B组（P＜0.05），β-EP水平升高，且C组高于A组与B组（P＜0.05）；三组患者治疗前简式疼痛量表（MPQ）与视觉模拟疼痛量表（VAS）评分对比无差异（P＞0.05），治疗后三组患者VAS、MPQ评分均降低，且C组低于A组与B组（P＜0.05）；三组患者治疗前脊柱功能指数量表（SFI）评分、Osweatry功能障碍指数（ODI）对比无差异（P＞0.05），治疗后三组患者SFI评分均升高，且C组高于A组与B组（P＜0.05），ODI指数均降低，且C组低于A组与B组（P＜0.05）。结论：针灸联合手法推拿比单一针灸与推拿更能够提升腰椎间盘突出症的治疗效果，且可降低炎症因子，提升?茁-内啡肽，减轻疼痛程度，进一步提升腰椎功能，值得临床应用推广。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effect of acupuncture and moxibustion combined with manual massage on lumbar disc herniation and plasma β- Endorphin（β- EP) and lumbar function. Methods: 102 patients with lumbar disc herniation admitted to our hospital from January 2020 to December 2022 were selected as the study subjects, and all patients were randomly divided into three groups: A (n=35), B (n=35), and C (n=32) using the random number table method. Group A patients were treated with acupuncture and moxibustion, Group B patients were treated with manual massage, and Group C patients were treated with acupuncture and moxibustion combined with manual massage. Compare the clinical efficacy of the three groups of patients, serum inflammatory factors and plasma before and Post-treatment for 1 month β- Endorphin expression level, pain level and lumbar function. Results: The total effective rate of group C was higher than that of group A and group B (P<0.05), but there was no difference between group A and group B (P>0.05); There was no difference in Tumor necrosis factor-α (TNF-α), matrix metalloproteinase-3 (MMP-3), interleukin-1 β (IL-1 β) and β -EP (P>0.05), TNF-α, MMP-3 and IL-1β were lower than group A and B (P<0.05), and β-EP was increased, and group C was higher than group A and B (P<0.05); There was no difference in the scores of MPQ and VAS Pretherapy among the three groups (P>0.05). Post-treatment, the VAS and MPQ scores of the three groups were lower, and the scores of Group C were lower than those of Group A and Group B (P<0.05); There was no difference in the scores of spinal function index (SFI) and Osweatry dysfunction index (ODI) among the three groups pretherapy (P>0.05). Post-treatment, the SFI scores of the three groups were increased, and group C was higher than group A and group B (P<0.05). The ODI index was lower, and group C was lower than group A and group B (P<0.05). Conclusion: Acupuncture and acupuncture combined with massage can improve the treatment effect of lumbar disc herniation, reduce the expression level of inflammatory factors in the body, improve the expression level of β-endorphins, reduce the pain degree of patients, and further improve the function of lumbar spine, which is worthy of clinical application and promotion. |
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