| 郑艳芝,董晓斐,谭甘露,李娇艳,成彩丽.点线面训练联合通督醒脑益肾健脾按摩对早产脑损伤患儿智力发育、运动发育和血清神经损伤标志物的影响[J].,2022,(24):4734-4737 |
| 点线面训练联合通督醒脑益肾健脾按摩对早产脑损伤患儿智力发育、运动发育和血清神经损伤标志物的影响 |
| Effects of Point, Line and Surface Training Combined with Tongdu Xingnao Yishen Jianpi Massage on Intellectual Development, Motor Development and Serum Markers of Nerve Injury in Premature Children with Brain Injury |
| 投稿时间：2022-05-23 修订日期：2022-06-18 |
| DOI：10.13241/j.cnki.pmb.2022.24.026 |
| 中文关键词: 点线面训练 通督醒脑益肾健脾按摩 早产儿 脑损伤 智力发育 运动发育 神经损伤标志物 |
| 英文关键词: Point line surface training Tongdu Xingnao Yishen Jianpi massage Premature children Brain damage Intellectual development Motor development Markers of nerve injury |
| 基金项目:湖南省卫生和计划生育委员会科研计划项目（C2016022）；湖南中医药大学中医学国内一流学科建设学科项目（4901-020002002）；湖南中医药大学第一附属医院院级课题（rsk-010-09） |
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| 中文摘要: |
| 摘要 目的：探讨点线面训练联合通督醒脑益肾健脾按摩对早产脑损伤患儿智力发育、运动发育和血清神经损伤标志物的影响。方法：选取2018年1月至2021年12月期间湖南中医药大学第一附属医院收治的92例早产脑损伤患儿，根据随机数字表法分为对照组和研究组，各为46例，对照组在常规治疗基础上结合点线面训练干预，研究组则在对照组的基础上结合通督醒脑益肾健脾按摩干预，观察两组患儿智力发育、运动发育和血清神经损伤标志物的变化情况。结果：干预3个疗程后，研究组社会适应、精细运动、大运动、个人社交、语言评分高于对照组（P<0.05）。干预3个疗程后，研究组卧位与翻身、坐位、爬和跪评分高于对照组（P<0.05）。干预3个疗程后，研究组血清糖分解烯醇酶（NSE）、胶质纤维酸性蛋白（GFAP）、S100钙结合蛋白β（S-100β）、髓鞘碱性蛋白（MBP）水平低于对照组（P<0.05）。结论：点线面训练联合通督醒脑益肾健脾按摩有助于改善早产脑损伤患儿智力发育、运动发育，并降低血清神经损伤标志物水平。 |
| 英文摘要: |
| ABSTRACT Objective: To explore the effect of point, line and surface training combined with Tongdu Xingnao Yishen Jianpi massage on intellectual development, motor development and serum markers of nerve injury in premature children with brain injury. Methods: 92 children with premature brain injury who were treated in our hospital from January 2018 to December 2021 were selected, they were randomly divided into control group and study group, with 46 cases in each group. The control group was intervened by point, line and surface training on the basis of routine treatment, and the study group was intervened by Tongdu Xingnao Yishen Jianpi massage on the basis of the control group. The changes of intelligence development, motor development and serum markers of nerve injury in the two groups were observed. Results: 3 courses after intervention, the scores of social adaptation, fine exercise, large exercise, personal social interaction and language in the study group were higher than those in the control group (P<0.05). 3 courses after intervention, the scores of lying position, turning over, sitting position, climbing and kneeling in the study group were higher than those in the control group (P<0.05). 3 courses after intervention, serum glycolytic enolase (NSE), glial fibrillary acidic protein (GFAP), S100β calcium binding protein （S-100β）, myelin basic protein (MBP) in the study group were lower than those of the control group (P<0.05). Conclusion: Point, line and surface training combined with Tongdu Xingnao Yishen Jianpi massage can improve the intellectual development and motor development of premature brain injury children, and reduce the level of serum markers of nerve injury. |
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