| 何 苗,孛立甲,曹志欧,郭宇新,冯 一.麻黄附子细辛汤配合缪刺法治疗腰椎间盘突出伴坐骨神经痛疗效及对VAS评分、JOA评分及炎症因子的影响[J].,2022,(13):2530-2534 |
| 麻黄附子细辛汤配合缪刺法治疗腰椎间盘突出伴坐骨神经痛疗效及对VAS评分、JOA评分及炎症因子的影响 |
| Effect of Ephedra Fuzi Asanxin Decoction Combined with Myobasmus in the Treatment of Lumbar Disc Herniation with Sciatica and Its Effect on VAS Score, JOA Score and Inflammatory Factors |
| 投稿时间：2022-01-08 修订日期：2022-01-31 |
| DOI：10.13241/j.cnki.pmb.2022.13.025 |
| 中文关键词: 麻黄附子细辛汤 缪刺法 腰椎间盘突出 坐骨神经痛 |
| 英文关键词: Mahuang Fuzi Xixin decoction Contralateral Needling Lumbar disc herniation Sciatica |
| 基金项目:北京中医药科技基金项目（JJ2019-34） |
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| 摘要 目的：探讨麻黄附子细辛汤配合缪刺法治疗腰椎间盘突出伴坐骨神经痛疗效及对视觉模拟评分（VAS）评分、日本骨科协会评估治疗分数（JOA）评分及炎症因子的影响。方法：2018年1月到2021年12月选择在本院诊治的腰椎间盘突出伴坐骨神经痛患者86例作为研究对象，据1:1随机分配数字表法把患者分为缪刺组与对照组各43例。对照组给予麻黄附子细辛汤治疗，缪刺组在对照组治疗的基础上给予缪刺治疗，所有患者都治疗观察1个月，在治疗前后进行VAS疼痛评分与JOA腰椎功能评分并分析炎症因子的表达情况。结果：治疗后缪刺组的总有效率为97.7 %，高于对照组的86.0 %（P<0.05）。两组治疗后的VAS评分与JOA评分低于治疗前，缪刺组低于对照组（P<0.05）。两组治疗后的腰屈曲范围高于治疗前，缪刺组高于对照组（P<0.05）。缪刺组治疗期间的腰大肌挛、恶心呕吐、低血压、眩晕等不良反应发生率为4.6 %，低于对照组的30.2 %（P<0.05）。两组治疗后的血清IL-1?琢、IL-6含量低于治疗前，缪刺组低于对照组（P<0.05）。结论：麻黄附子细辛汤配合缪刺法治疗腰椎间盘突出伴坐骨神经痛能降低患者的VAS评分与JOA评分，可减少不良反应的发生，还可抑制炎症因子的表达，提高患者的腰屈曲范围。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the curative effect of Mahuang Fuzi Xixin Decoction combined with Miao needling in the treatment of lumbar intervertebral disc herniation with sciatica and its effect on visual analogue scale (VAS) score, the Japanese Orthopaedic Association Scores (JOA) score and the inflammatory factors. Methods: From January 2018 to December 2021, 86 cases of patients with lumbar intervertebral disc herniation and sciatica who were diagnosed and treated in our hospital were selected as the research subjects. All the cases were divided into the Miao acupuncture group and the control group of 43 cases in each groups accorded to the 1:1 random allocation number table method. The control group were given Mahuang Fuzi Xixin Decoction, and the Miao needling group were given Miao needling on the basis of the treatment of the control group. All patients were observed for 1 month. VAS pain score and JOA lumbar function score were performed before and after treatment, and the expression of inflammatory factors was analyzed. Results: After treatment, the total effective rates of Miao needling group were 97.7 %, which were higher than 86.0 % of control group (P<0.05). The VAS and JOA scores of the two groups after treatment were lower than those before treatment, and the Miao needling group were lower than that of the control group(P<0.05). The range of lumbar flexion in the two groups after treatment were higher than that before treatment, and that in the miao needling group were higher than that in the control group(P<0.05). The incidence of psoas major, nausea and vomiting, hypotension, dizziness and other adverse reactions in the miao needling group were 4.6 %, which were lower than 30.2 % in the control group(P<0.05). The levels of serum IL-1α and IL-6 in the two groups after treatment were lower than those before treatment, and those in the Miao needling group were lower than those in the control group(P<0.05). Conclusion: Mahuang Fuzi Xixin Decoction combined with Miao needling in the treatment of lumbar intervertebral disc herniation with sciatica can reduce the VAS score and JOA score of patients, reduce the occurrence of adverse reactions, inhibit the expression of inflammatory factors, and improve the lumbar flexion range of patients. |
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