| 周 昶,张永志,张 丁,邓雪峰,陶 清.超快通道麻醉对胸腔镜手术患者血流动力学与血清干扰素的影响[J].,2021,(21):4083-4086 |
| 超快通道麻醉对胸腔镜手术患者血流动力学与血清干扰素的影响 |
| Effect of Ultrafast Channel Anesthesia on Hemodynamics and Serum Interferon in Patients Undergoing Thoracoscopic Surgery |
| 投稿时间：2021-01-29 修订日期：2021-02-25 |
| DOI：10.13241/j.cnki.pmb.2021.21.017 |
| 中文关键词: 超快通道麻醉 胸腔镜 血流动力学 干扰素-γ |
| 英文关键词: Ultrafast channel anesthesia Thoracoscopy Hemodynamics Interferon-γ |
| 基金项目:国家重点专科开放性课题项目（2016zkkf006） |
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| 中文摘要: |
| 摘要 目的：探讨超快通道麻醉对胸腔镜手术患者血流动力学与血清干扰素-γ(Interferon-γ，IFN-γ)的影响。方法：选择2018年1月~2020年10月在安徽中医药大学第一附属医院诊治的胸腔镜手术患者62例，根据治疗方法分为两组（n=31），患者均行胸腔镜手术，对照组给予传统静脉复合麻醉，实验组给予超快通道麻醉，记录两组血流动力学与血清IFN-γ变化。结果：两组T0、T1、T2与T3时间点的平均动脉压(Mean arterial pressure，MAP)、心率(Heart rate，HR)值对比无差异(P>0.05)，均在正常范围。两组手术时间、术中出血量对比无差异(P>0.05)，实验组术后胸管留置时间、住院时间短于对照组(P<0.05)。实验组术后7 d并发症发生率低于对照组(6.5 % vs 25.8 %，P<0.05)。两组术后7 d的血清IFN-γ值高于术前1 d，且实验组高于对照组(P<0.05)。结论：超快通道麻醉在胸腔镜手术患者的应用并不会影响患者的血流动力学与手术进程，有利于抑制血清IFN-γ的释放，减少术后并发症的发生，促进患者康复。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of ultrafast channel anesthesia on hemodynamics and serum interferon-γ (IFN-γ) in patients undergoing thoracoscopic surgery. Methods: A total of 62 patients undergoing thoracoscopic surgery in the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from January 2018 to October 2020 were selected and divided into two groups according to the treatment method (n=31). All patients underwent thoracoscopic surgery, the control group were given traditional intravenous combined anesthesia, and the experimental group were given ultra-fast channel anesthesia. The changes in hemodynamics and serum IFN-γ expression were recorded. Results: There was no difference in the mean arterial pressure (MAP) and heart rate (HR) values between the two groups at T0, T1, T2 and T3(P>0.05), and they were all within the normal range. There was no difference in operation time and intraoperative blood loss between the two groups(P>0.05). The postoperative chest tube indwelling time and hospital stay in the experimental group were shorter than those in the control group(P<0.05). The complication rate of the experimental group was lower than that of the control group (6.5% vs 25.8 %, P<0.05). Serum IFN-γ values of the two groups at 7 days after operation were higher than those at 1 day before operation, and the experimental group was higher than the control group (P<0.05). Conclusion: The application of ultrafast channel anesthesia in patients undergoing thoracoscopic surgery does not affect the patient's hemodynamics and surgical process, and is beneficial to inhibit the release of serum IFN-γ, reduce postoperative complications, and promote patient recovery. |
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