| 贺荣荣,张京京,袁小华,樊阳阳,张莉莉.个体化饮食控制联合参芪降糖颗粒对妊娠期糖尿病的疗效[J].,2021,(3):485-488 |
| 个体化饮食控制联合参芪降糖颗粒对妊娠期糖尿病的疗效 |
| Effect of Individualized Diet Control Combined with Shenqi Jiangtang Granule on the Gestational Diabetes Mellitus |
| 投稿时间：2020-03-07 修订日期：2020-03-31 |
| DOI：10.13241/j.cnki.pmb.2021.03.017 |
| 中文关键词: 个体化饮食控制 参芪降糖颗粒 妊娠期糖尿病 |
| 英文关键词: Individualized diet control Shenqi Jiangtang granules Gestational diabetes mellitus |
| 基金项目:国家自然科学基金项目(81200418) |
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| 中文摘要: |
| 摘要 目的：研究个体化饮食控制联合参芪降糖颗粒对妊娠期糖尿病的疗效。方法：选择2016年1月～2018年12月我院收治的201例妊娠期糖尿病患者，将其随机分为两组。对照组采用个体化饮食控制，观察组在个体化饮食控制的基础上加用参芪降糖颗粒，每次口服1 g，每天3次。比较两组治疗前后的餐后2 h血糖、胰岛β细胞功能指数(homeostasis model assessment-β, HOMA-β)及空腹血糖的变化，妊娠不良结局和围产期并发症的发生情况。结果：治疗后，观察组的降糖有效率为95.00 %，明显高于对照组(75.24 %，P<0.05)；两组的HOMA-β较治疗前明显升高(P<0.05)，餐后2 h血糖及空腹血糖均较治疗前明显降低(P<0.05)，且观察组上述指标变化优于对照组(P<0.05)。观察组的早产率为2.00 % (2/100)、剖宫产率为29.00 % (29/100)、晚期流率为3.00 % (3/100)，均明显低于对照组(P<0.05)。观察组的新生儿低血糖、胎儿窘迫、羊水过多、产褥期感染以及产后出血发生率为7.00 %，明显低于对照组(21.78 %，P<0.05)。结论：个体化饮食控制联合参芪降糖颗粒对妊娠期糖尿病疗效明显优于单用个体化饮食控制，其能有效改善妊娠结局，减少围产期的并发症。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of individualized diet control combined with Shenqi Jiangtang Granule on the gestational diabetes mellitus. Methods: 201 patients with gestational diabetes mellitus who admitted to our hospital from January 2016 to December 2018 were selected and randomly divided into two groups. The control group was treated with individualized diet control, while the observation group was treated with Shenqi Jiangtang granules on the basis of individualized diet control, 1g every time, 3 times a day. The changes in postprandial blood glucose, homeostasis model assessment-β (HOMA-β), fasting blood glucose, adverse pregnancy outcomes, and perinatal complications were compared between the two groups before and after treatment. Results: After treatment, the effective rate of reducing blood glucose in the observation group was 95.00 %, which was significantly higher than in the control group (75.24%, P<0.05). The HOMA-β of both groups were significantly higher than those before treatment (P<0.05), and the blood glucose at 2 h after meal and fasting blood glucose were significantly lower than before treatment (P<0.05), and the above indicators in the observation group were better than those in the control group (P<0.05). The preterm delivery rate in the observation group was 2.00 % (2/100), the cesarean section rate was 29.00 % (29/100), the late flow rate was 3.00 % (3/100), which were significantly lower than those in the control group (P<0.05). The incidence rate of neonatal hypoglycemia, fetal distress, polyhydramnios, postpartum infection and postpartum hemorrhage in the observation group was 7.00 % , which were significantly lower than those in the control group (21.78 %, P<0.05). Conclusion: Individualized diet control combined with Shenqi Jiangtang granules is significantly better thanindividualized diet control alone for the on gestational diabetes, which can effectively improve the pregnancy outcomes and reduce the perinatal complications. |
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