| 董瑞丽,马宏生,何金英,伊丽奇,赵 娟.阴道镜及宫颈活组织检查对早期宫颈上皮内瘤变诊断价值分析[J].,2020,(8):1528-1531 |
| 阴道镜及宫颈活组织检查对早期宫颈上皮内瘤变诊断价值分析 |
| Diagnostic Value of Colposcopy and Cervical Biopsy for Early Cervical Intraepithelial Neoplasia |
| 投稿时间：2019-12-01 修订日期：2019-12-24 |
| DOI：10.13241/j.cnki.pmb.2020.08.028 |
| 中文关键词: 阴道镜 宫颈活组织 早期宫颈上皮内瘤变 诊断价值 分析 |
| 英文关键词: Colposcopy Cervical biopsy Early cervical intraepithelial neoplasia Diagnostic value Analysis |
| 基金项目:内蒙古自治区自然科学基金项目(2017MS08140 ) |
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| 摘要 目的：探究阴道镜及宫颈活组织检查对早期宫颈上皮内瘤变（cervicalintraepithelialneoplasia，CIN）的诊断价值。方法：选择2015年3月至2018年5月于我院接受诊治的543例疑似宫颈上皮瘤变患者，分别对其实施阴道镜及宫颈活组织检查，以病理学检测结果为金标准，分别评估两种方式单独检测及联合检测对早期CIN的诊断一致性、灵敏度和特异度，并进行组间对比。结果：（1）543例疑似CIN患者病理诊断早期CIN阳性患者168例，阴性患者375例，诊断率为30.94 %；阴道镜对早期CIN诊断发现阳性患者有143例，良性患者有400例，诊断率为26.34 %；宫颈活组织检测对早期CIN诊断发现阳性患者有159例，良性患者有384例，诊断率为29.28 %；阴道镜联合颈活组织检测对早期CIN诊断发现阳性患者有163例，良性患者有380例，诊断率为30.02 %。（2）检测发现，阴道镜对早期CIN诊断一致性为81.77 %，灵敏度为60.12 %，特异度为91.47 %。（3）宫颈活组织对早期CIN诊断一致性为91.71 %，灵敏度为83.33 %，特异度为95.47 %。（4）阴道镜联合宫颈活组织对早期CIN诊断一致性为96.50 %，灵敏度为92.86 %，特异度为98.13 %。（5）联合检测对早期CIN诊断的一致性、灵敏度和特异度均明显优于阴道镜及宫颈活组织单独检测。结论：阴道镜及宫颈活组织检测对早期CIN具有较好的诊断效果，但联合检测诊断准确率更高，适用于早期CIN临床筛查中。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the diagnostic value of colposcopy and cervical biopsy for early cervical intraepithelial neoplasia (CIN). Methods: 543 patients with suspected cervical epithelial tumors who were treated in our hospital from March 2015 to May 2018 For the study subjects, colposcopy and cervical biopsy were performed respectively, and the results of pathological examination were used as the gold standard. The consistency, sensitivity and specificity of the two methods of single detection and combined detection for early CIN were evaluated and performed. Comparison between groups. Results: (1) 543 patients with suspected CIN were diagnosed with 168 early CIN-positive patients and 375 negative patients, the diagnosis rate was 30.94 %. Colposcopy was positive for early CIN diagnosis in 143 patients and benign patients in 400 cases, the diagnosis rate was 26.34 %. Cervical biopsy showed 159 positive CIN patients and 384 benign patients, the diagnosis rate was 29.28 %. Colposcopy combined with cervical biopsy detected 163 positive CIN patients and 380 benign patients, the diagnosis rate was 30.02 %. (2) The consistency of colposcopy for early CIN diagnosis was 81.77 %, the sensitivity was 60.12 %, and the specificity was 91.47 %. (3) The consistency of cervical biopsy for early CIN was 91.71 %, and the sensitivity was 83.33 %. The degree was 95.47 %. (4) the consistency of colposcopy combined with cervical biopsy for early CIN was 96.50 %, the sensitivity was 92.86 %, and the specificity was 98.13 %. (5) The consistency and sensitivity of combined detection for early CIN diagnosis Obviously better than colposcopy and cervical biopsy. Conclusion: Colposcopy and cervical biopsy have a good diagnostic effect on early CIN, but the combined detection has a higher accuracy and is suitable for early CIN clinical screening. |
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