| 李晓杰,李新辉,袁利和,王 瑾,林立荣,曹胜军.神经电生理刺激对脑卒中患者脊髓运动神经元的影响[J].,2020,(8):1493-1496 |
| 神经电生理刺激对脑卒中患者脊髓运动神经元的影响 |
| Effect of Neurophysiological Stimulation on Spinal Motor Neurons in Stroke Patients |
| 投稿时间：2019-10-04 修订日期：2019-10-30 |
| DOI：10.13241/j.cnki.pmb.2020.08.020 |
| 中文关键词: 神经电生理刺激 脑卒中 脊髓运动 神经元 脑电活动功能 |
| 英文关键词: Neurophysiological stimulation Stroke Spinal cord movement Neuron Brain electrical activity |
| 基金项目:内蒙古自治区自然科学基金项目（2016MS0811） |
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| 中文摘要: |
| 摘要 目的：探讨神经电生理刺激对脑卒中患者脊髓运动神经元的影响。方法：2015年9月至2018年2月选择在本院神经内科病房诊治的脑卒中患者160例，根据入院顺序随机分为研究组与对照组，各80例。对照组给予常规治疗，研究组在对照组治疗的基础上给予神经电生理刺激治疗，两组都治疗观察14 d，记录脊髓运动神经功能变化情况。结果：两组治疗后14 d，患者的认知障碍、焦虑抑郁情绪、双下肢无力，步态不稳均得到了改善，研究组的一般情况的改善情况更加明显，主要体现在认知和情绪方面。两组治疗14 d后的脊髓运动神经评分都显著高于治疗前(P<0.05)，研究组也显著高于对照组(P<0.05)。治疗后两组的脑电诱发电位波幅都显著高于治疗前(P<0.05)，研究组也显著高于对照组(P<0.05)，两组治疗前后潜伏期对比差异无统计学意义(P>0.05)。研究组治疗期间的肺部感染、颅内感染、迟发性颅内血肿等并发症发生率为3.8 %，对照组为5.0 %，对比差异无统计学意义(P>0.05)。随访至今(2019年8月)，研究组的预后恢复情况显著好于对照组(P<0.05)。结论：电生理刺激在脑卒中患者的应用能促进恢复脊髓运动神经元功能，改善脑电活动功能，提高认知功能，减少并发症和焦虑情绪的发生，改善患者的预后恢复。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effects of neurophysiological stimulation on spinal motor neurons in stroke patients. Methods: From September 2015 to February 2018, 160 patients with stroke who were treated in the neurology department of our hospital were randomly divided into the study group and control group accorded to the order of admission, 80 cases each. The control group received routine treatment, and the study group received neuroelectrophysiological stimulation on the basis of the control group. Two groups were treated for 14 d, and the changes of spinal motor nerve function were recorded. Results: At 14 d after treatment, the cognitive impairment, anxiety and depression, weakness of both lower limbs, and gait instability were improved. The improvement of the general situation of the study group was more obvious, mainly in terms of cognition and emotion. The spinal motor nerve scores of the two groups after treatment for 14 d were significantly higher than those before treatment (P<0.05), and the study group was significantly higher than the control group (P<0.05). The EEG evoked potential amplitudes of the two groups after treatment were significantly higher than those before treatment (P<0.05), and the study group was also significantly higher than the control group (P<0.05). There were no statistical difference in latency between the two groups before and after treatment (P>0.05). The incidence of complications such as pulmonary infection, intracranial infection, and delayed intracranial hematoma was 3.8 % in the study group and 5.0 % in the control group, there was no significant difference between the two groups (P>0.05). After the followed-up (August 2019), the prognosis of the study group were significantly better than the control group (P<0.05). Conclusion: The application of neuroelectrophysiological stimulation in stroke patients can promote the recovery of spinal motor neuron function, improve the function of EEG activity, improve cognitive function, reduce the occurrence of complications and anxiety, and improve the prognosis of patients. |
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