| 陈爱德,刘伟军,段王栋,邹 林,胡亚恒,魏文存.256层螺旋CT前瞻性心电门控冠状动脉成像的临床应用价值及其对比剂浓度研究[J].,2019,19(20):3963-3967 |
| 256层螺旋CT前瞻性心电门控冠状动脉成像的临床应用价值及其对比剂浓度研究 |
| Clinical Application Value of Prospective Electrocardiogram-controlled Coronary Artery Imaging with 256-slice Spiral CT and the Study of Contrast Agent Concentration |
| 投稿时间：2019-05-08 修订日期：2019-05-31 |
| DOI：10.13241/j.cnki.pmb.2019.20.037 |
| 中文关键词: 前瞻性心电门控技术 回顾性心电门控技术 冠状动脉成像 对比剂 浓度 |
| 英文关键词: Prospective electrocardiogram-controlled technology Retrospective electrocardiogram-controlled technology Coronary artery imaging Contrast agent Concentration |
| 基金项目:陕西省创新能力支撑计划项目（2017KCT-36） |
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| 中文摘要: |
| 摘要 目的：探讨256层螺旋CT前瞻性心电门控冠状动脉成像的临床应用价值及不同浓度对比剂对其成像质量、碘用量以及有效辐射剂量的影响。方法：对120例疑似冠心病患者行256层螺旋CT成像扫描，将患者随机分为前瞻性心电门控组和回顾性心电门控组；出院前再将前瞻性心电门控组患者按数表法随机分为低浓度对比剂组、中浓度对比剂组和高浓度对比剂组。比较各组成像质量、碘用量、有效辐射剂量。结果：前瞻性心电门控组与回顾性心电门控组图像质量主观评分分布、可评价节段率、优良率、有效碘用量、信噪比（SNR）、载噪比（CNR）、主动脉CT值(CT主)、主动脉噪声值（SD主）比较无统计学差异（P>0.05）。前瞻性心电门控组有效辐射剂量显著低于回顾性心电门控组（P<0.05）。高浓度对比剂组可评价节段率、优良率、有效碘用量、SNR、CNR、CT主显著高于低浓度对比剂组和中浓度对比剂组（P＜0.05），中浓度对比剂组CNR显著高于低浓度对比剂组（P＜0.05）。结论：前瞻性心电门控技术用于冠心病诊断的图像质量与回顾性心电门控技术无明显差异，但是前瞻性心电门控技术辐射剂量更低。前瞻性心电门控使用低浓度对比剂可以获得满足临床诊断需要的图像质量，且碘用量更少。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate clinical application value of prospective electrocardiogram-controlled coronary artery imaging with 256-slice spiral CT and the effect of different concentration of contrast agent on imaging quality, iodine dosage and effective radiation dose. Methods: 120 patients with suspected coronary heart disease were scanned with 256-slice spiral CT. The patients were randomly divided into prospective electrocardiogram-controlled group and retrospective electrocardiogram-controlled group. Before discharge, the prospective electrocardiogram-controlled group was randomly divided into low concentration contrast agent group, medium concentration contrast agent group and high concentration contrast agent group according to the number table method. The image quality, iodine dosage and effective radiation dose of each component were compared. Results: There were no significant differences in subjective image quality score distribution, assessable segment rate, excellent and good rate, effective iodine dosage, signal-to-noise ratio(SNR), carrier-to-noise ratio (CNR), aortic CT value (CT aorta) and aortic noise value (SD aorta) between the prospective electrocardiogram-controlled group and retrospective electrocardiogram-controlled group (P>0.05). The effective radiation dose in prospective electrocardiogram-controlled group was significantly lower than that in retrospective electrocardiogram-controlled group (P<0.05). The assessable segmental rate, excellent and good rate, effective iodine dosage, SNR, CNR and CT aorta in high concentration contrast agent group were significantly higher than those in low concentration contrast agent group and medium concentration contrast agent group (P<0.05). CNR in medium concentration contrast agent group was significantly higher than that in low concentration contrast agent group (P<0.05). Conclusion: The image quality of prospective electrocardiogram-controlled technology in diagnosis of coronary heart disease is not significantly different from that of retrospective electrocardiogram-controlled technology, but the radiation dose of prospective electrocardiogram-controlled technology is lower. Prospective electrocardiogram-controlled with low concentration contrast agent can achieve image quality that meets the needs of clinical diagnosis, and iodine consumption is less. |
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