| 刘 刚,魏秀玲,谢占玉,刘 芳,马莹莹.微创小切口主动脉瓣置换术对主动脉瓣狭窄患者临床效果、心功能及术后时间的影响[J].,2019,19(19):3768-3771 |
| 微创小切口主动脉瓣置换术对主动脉瓣狭窄患者临床效果、心功能及术后时间的影响 |
| Effect of Minimally Invasive Small Incision Aortic Valve Replacement on Clinical Outcome, Cardiac Function and Postoperative Time in Patients with Aortic Stenosis |
| 投稿时间：2019-02-26 修订日期：2019-03-21 |
| DOI：10.13241/j.cnki.pmb.2019.19.039 |
| 中文关键词: 主动脉瓣置换术 微创小切口 主动脉瓣狭窄 心功能 生活质量 |
| 英文关键词: Aortic valve replacement Minimally invasive small incision Aortic stenosis Cardiac function Quality of life |
| 基金项目:青海省卫生计生委科研项目（2016WJDZX136） |
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| 中文摘要: |
| 摘要 目的：探讨微创小切口主动脉瓣置换术对主动脉瓣狭窄患者临床效果、心功能及术后时间的影响。方法：选择2017年5月-2018年11月我院收治的98例患者，随机分为观察组（n=49）和对照组（n=49）。对照组患者给予传统开胸主动脉瓣置换术，观察组患者给予微创小切口主动脉瓣置换术。观察比较两组临床疗效，心功能指标变化，术后时间变化。结果：观察组有效率为93.88%，明显高于对照组71.43%，两组疗效比较差异有统计学意义（P<0.05）。观察组术后左室射血分数（LVEF）、左室舒张末期直径（LVEDD）、平均跨瓣压差（MVPG）明显低于对照组，差异均具有统计学意义（P<0.05）；观察组术室间隔厚度（IVST）高于对照组，但差异无统计学意义（P>0.05）。观察组术后机械通气时间，ICU时间，住院时间明显低于对照组，差异均具有统计学意义（P<0.05）。结论：微创小切口主动脉瓣置换术治疗主动脉瓣狭窄临床疗效显著，可有效改善患者心功能，缩短治疗时间，提高患者生活质量，值得推广应用。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the effect of minimally invasive small incision aortic valve replacement on clinical outcome, cardiac function and postoperative time in patients with aortic stenosis. Methods: 98 patients admitted to our hospital from May 2017 to November 2018 were randomly divided into observation group (n=49) and control group (n=49). Patients in the control group were treated with traditional thoracotomy aortic valve replacement, while patients in the observation group were treated with minimally invasive small incision aortic valve replacement. To observe and compare the clinical efficacy, changes of cardiac function and time after operation between the two groups. Results: The effective rate of the observation group was 93.88%, which was significantly higher than 71.43% in the control group, there was a significant difference between the two groups (P<0.05). The left ventricular ejection fraction (LVEF), left ventricular end-diastolic diameter (LVEDD) and mean transvalvular pressure difference (MVPG) in the observation group were significantly lower than those in the control group (P<0.05), and the interventricular septum thickness (IVST) in the observation group was higher than that in the control group, but there was no significant difference (P>0.05). The duration of mechanical ventilation, ICU and hospitalization in the observation group were significantly lower than those in the control group (P<0.05). Conclusion: Minimally invasive small incision aortic valve replacement has remarkable clinical effect in the treatment of aortic stenosis, which can effectively improve the cardiac function, shorten the treatment time and improve the quality of life of patients, and it is worth popularizing and applying. |
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