| 徐 嵘,王大佳,张 伟,王 宏,王 伟.思连康联合蒙脱石散治疗小儿急性肠炎的疗效和对血清IgG、IgA、IgM水平的影响[J].,2019,19(11):2140-2143 |
| 思连康联合蒙脱石散治疗小儿急性肠炎的疗效和对血清IgG、IgA、IgM水平的影响 |
| Efficacy of Si Liankang Combined with Montmorillonite in the Treatment of Children with Pediatric Acute Enteritis and its Effect on the Serum IgG, IgA, IgM Levels |
| 投稿时间：2018-10-25 修订日期：2018-11-19 |
| DOI：10.13241/j.cnki.pmb.2019.11.029 |
| 中文关键词: 思连康 蒙脱石散 急性肠炎 疗效 免疫功能 |
| 英文关键词: Si Liankang Montmorillonite Pediatric acute enteritis Efficacy Immune function |
| 基金项目:辽宁省自然科学基金项目(2014J0226) |
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| 中文摘要: |
| 摘要 目的：探讨思连康联合蒙脱石散治疗小儿急性肠炎的临床疗效和对血清IgG、IgA、IgM水平的影响。方法：选择我院2016年8至2017年8月收治的86例小儿急性肠炎患儿，根据随机数字表法将其随机分为观察组及对照组，两组患儿均给予常规治疗，对照组患儿在常规治疗基础上给予蒙脱石散治疗，观察组在对照组基础上给予思连康治疗。观察和比较两组患儿治疗后的疗效、呕吐缓解时间、发热消退时间、大便恢复正常时间、腹痛缓解时间、粪便常规恢复正常的时间及两组治疗前后的血清IgG、IgA、IgM水平的变化情况。结果：治疗后，观察组和对照组的总有效率分别为95.2%(40/42)、79.5%(35/44)，观察组总有效率显著明显高于对照组(P<0.05)；观察组患儿的呕吐缓解时间、发热消退时间、大便恢复正常时间、腹痛缓解时间及粪便常规恢复正常的时间均明显短于对照组(P<0.05)。治疗后，两组患儿的血清IgG、IgA、IgM水平均较治疗前明显升高，且观察组治疗后血清IgG、IgA、IgM水平均明显高于对照组(P<0.05)。结论：与单用蒙脱石散治疗相比，思连康联合蒙脱石散治疗小儿急性肠炎可有效提高治疗效果，缩短患儿临床症状改善时间，提高患儿免疫力。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the clinical efficacy of Si Liankang combined with montmorillonite in the treatment of chil- dren with pediatric acute enteritis and its effect on the serum IgG, IgA and IgM levels. Methods: 86 cases with pediatric acute enteritis from August 2016 to August 2017 in our hospital were selected and divided into the observation group and control group according to random number table method, both groups were given conventional treatment, the control group was given montmorillonite on the basis of conventional treatment, the observation group was given Si Liankang on the basis of control group. The curative effect, remission time of vomiting, remission time of fever, recovery time of stool, abdominal pain relief time, routine recovery time of stool were observed and compared between the two groups. And the changes of serum IgG, IgA and IgM levels before and after treatment were observed and compared between the two groups. Results: After treatment, the total effective rate of observation group and the control group were 95.2% (40/42) and 79.5% (35/44), respectively, which was significantly higher in the observation group than that of the control group (P<0.05). The remission time of vomiting, fever subsidence time, fecal recovery time, abdominal pain relief time and fecal routine recov- ery time of observation group were significantly shorter than those of the control group (P<0.05). After treatment, the levels of serum IgG, IgA and IgM in both groups were significantly higher than those before treatment, and the levels of serum IgG, IgA and IgM in the observation group were significantly higher than those in the control group (P<0.05). Conclusion: Compared with montmorillonite alone, Siliankang combined with montmorillonite can effectively improve the therapeutic effect, shorten the improvement time of clinical symp- toms and improve the immunity of children with acute enteritis. |
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