| 叶 钢,赵立涵,刘 立,蒋 波,李 宾,姜 健.连续性肾脏替代治疗与间歇性血液透析对急性肾损伤的临床疗效比较[J].,2017,17(21):4172-4174 |
| 连续性肾脏替代治疗与间歇性血液透析对急性肾损伤的临床疗效比较 |
| Comparison of the Clinical Effects of Continuous Renal Replacement Therapy and Intermittent Hemodialysis on Acute Renal Injury |
| 投稿时间：2016-11-14 修订日期：2016-11-30 |
| DOI：10.13241/j.cnki.pmb.2017.21.043 |
| 中文关键词: 急性肾损伤 血液透析 肾脏替代治疗 心血管事件 |
| 英文关键词: Acute renal injury Intermittent hemodialysis Renal replacement therapy Cardiovascular events |
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| 摘要 目的：比较连续性肾脏替代治疗与间歇性血液透析对急性肾损伤的临床疗效。方法：回顾性分析从2014年2月到2016年2月来我院治疗的急性肾损伤患者50例，按照治疗方法分为连续性肾脏替代治疗(Continuous renal replacement therapy，CRRT)组与间歇性血液透析(Intermittent hemodialysis，IHD)组，每组各25例。记录两组治疗前的基线数据，治疗前与治疗后的血清C-反应蛋白(C-reactive protein，CRP)、血肌酐(Serum creatinine，SCr)含量以及尿量恢复时间、重症监护室(Intensive care unit，ICU)住院时间、心血管事件发生率。结果：CRRT组与IHD组治疗前的一般资料以及尿量、血清CRP、SCr水平比较差异均无统计学意义(P>0.05)。治疗1周后，与IHD组相比，CRRT组血清CRP、SCr水平明显下降，尿量恢复时间、ICU住院时间均明显缩短，心血管发生率(32.0 % vs. 64.0 %)明显下降，差异均具有统计学意义(P<0.05)。结论：CRRT治疗急性肾损伤能有效改善患者肾功能，缩短ICU住院时间并提高治疗安全性。 |
| 英文摘要: |
| ABSTRACT Objective: To compare the clinical effects of continuous renal replacement therapy and intermittent hemodialysis in the treatment of acute renal injury. Methods: 50 cases of patients with acute kidney injury in our hospital from February 2014 to February 2016 were selected, and equally divided into the continuous renal replacement therapy (CRRT) group (n=25) and intermittent hemodialy- sis(IHD) group(n=25) according to the treatment. The baseline data, serum levels of C-reactive protein (CRP) and serum creatinine (SCr) before and at 1 week after treatment, the time of recovery of urine volume, the length of ICU stay, and the incidence of cardiovascular events were observed and compared between two groups. Results: There was no statistically significant difference in the urine volume, serum CRP, and SCr levels before treatment between IHD group and CRRT group (all P > 0.05). At one week after treatment, compared to the IHD group, CRRT could dramatically reduce the serum levels of CRP, SCr levels, urine output recovery time, the length of ICU stay, and the incidence of cardiovascular events (32.0 % vs. 64.0 %) (all P<0.05). Conclusion: CRRT could more efficiently improve the renal function, shorten the length of ICU stay and enhance the safety on patients with AKI. |
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