| 王晓艳,田宗梅,宁慧宇,王学艳,李晓荣.季节因素对过敏性结膜炎就诊及用药的影响研究[J].,2017,17(18):3473-3476 |
| 季节因素对过敏性结膜炎就诊及用药的影响研究 |
| Influence of Seasonal Factors on Treatment and Medication of Allergic Conjunctivitis |
| 投稿时间：2017-03-02 修订日期：2017-03-28 |
| DOI：10.13241/j.cnki.pmb.2017.18.016 |
| 中文关键词: 气传花粉 过敏性结膜炎 季节性过敏性结膜炎 抗过敏滴眼液 季节因素 |
| 英文关键词: Airborne pollen Allergic conjunctivitis Seasonal allergic conjunctivitis Anti-allergic eye drops Seasonal factor |
| 基金项目:北京市科技计划基金项目（Z161100000516006) |
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| 中文摘要: |
| 摘要 目的：探讨过敏性结膜炎（AC）与抗过敏滴眼液用量间的关系，并分析季节因素对其产生的影响。方法：采用重力沉降法于2015年全年对北京城区主要气传花粉浓度进行监测，统计2015年我院变态反应科门诊AC就诊诊次及三种主要抗过敏滴眼液处方量，并采用Spearman相关性分析AC就诊诊次与抗过敏滴眼液用量间的关系。结果：2015年全年共监测花粉76164颗，花粉分布呈现春秋两季高峰，花粉分布最高的月份为4月（34.84%），其次为3月（29.72%），5月（10.87%），9月（10.52%），8月（9.94%）；花粉分布最少的月份为1月和11月（0.11%）。春季花粉高峰期（3-5月份）月平均花粉数量为19150颗，秋季花粉高峰期（8-9月份）月平均花粉数量为7792颗，秋季花粉高峰期月平均花粉数量低于春季。2015年我院变态反应科AC月平均就诊诊次为（80.42± 54.28）人次，8月份AC诊次最高，占全年的18.03%，其次为9月份（16.99%）、4月份（13.99%）、3月份（12.54%）、5月份（7.98%）。抗过敏滴眼液月平均用量为（148.67±148.63）瓶，8月份抗过敏滴眼液用量最高，占全年的28.25%，其次为3月份（17.21%）、9月份（14.18%）、4月份（13.11%）、5月份（8.30%），AC就诊次数及抗过敏滴眼液处方量均呈现春秋季节高峰。Spearman相关性分析显示，每月花粉量与AC就诊诊次、抗过敏滴眼液用量呈正相关（r=0.806，0.830，P=0.000，0.000），AC就诊诊次与抗过敏滴眼液用量呈正相关（r=0.923，P=0.000）。结论：花粉分布、AC诊次及抗过敏滴眼液用量均出现春秋季节高峰。秋季花粉致敏性高于春季花粉，用药及AC就诊最高峰均出现在秋季。 |
| 英文摘要: |
| ABSTRACT Objective: To investigate the relationship between the dosage of allergic conjunctivitis (AC) and anti allergic eye drops, and to analyze the influence of seasonal factors on it. Methods: The concentration of airborne pollen was monitored by gravitational sedimentation method in Beijing city in the whole year of 2015. The number of allergy department for AC visits and the dosage of three major anti allergic eye drops in Beijing Shijitan Hospital in 2015 were counted,and the relationship between the number of AC visits and the dosage of anti allergic eye drops were analyzed by using Spearman correlation analysis. Results: In the whole year of 2015, a total of 76164 pollen was monitored. Pollen distribution showed two peaks in Spring and Autumn. The number of pollen in April was the most (34.84%), followed by March (29.72%), May (10.87%), September (10.52%), August (9.94%), and the least pollen months were January and November (0.11%). The average number of pollen was 19150 in the peak period of Spring pollen from March to May,the average number of pollen was 7792 in the peak period of Autumn pollen from August to September, and the average number of pollen in Autumn was lower than that in Spring. In 2015, the average monthly visit rate of AC in the hospital was (80.42±54.28), AC was the highest in August, accounting for 18.03% of the year, followed by September (16.99%), April (13.99%), March (12.54%), May (7.98%). The average dosage of anti allergic eye drops was (148.67±148.63) bottle, the highest dosage of anti allergy eye drops was in August, accounting for 28.25%, followed by March (17.21%), September (14.18%), April (13.11%), May (8.30%), and the number of AC visits and the dosage of anti allergic eye drops showed Spring and Autumn peak. Spearman correlation analysis showed that there was a positive correlation between the amount of pollen and the number of AC visits and the dosage of anti allergic eye drops(r=0.806, 0.830, P=0.000, 0.000), and there was a positive correlation between the number of AC visits and the dosage of anti allergic eye drops(r=0.923, P=0.000). Conclusion: The distribution of pollen, the number of AC visits and the dosage of anti allergic eye drops all appear Spring and Autumn peak. The pollen sensitization in Autumn is higher than that in Spring, and the peaks of medication and AC visits are in Autumn. |
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